Based on the results from the MATTERHORN (A Multicenter, Randomized, Controlled Study to Assess Mitral Valve Reconstruction for Advanced Insufficiency of Functional or Ischemic Origin), transcatheter ...

However, there are key differences in the studies that make a 1:1 comparison difficult. For one, the patients in the RESHAPE-HF2 trial had less severe mitral valve regurgitation than did those in the ...

4 The MITHRAS trial (Closure of Iatrogenic Atrial Septal Defects Following Transcatheter Mitral Valve Repair) is an investigator-initiated, single-center, randomized, open-label trial conducted at the ...

Background Although the prognostic implications of severe mitral regurgitation (MR) are well recognised, they are less clear in moderate MR. We therefore explored the prognostic impact of both ...

The mitral valve allows blood to flow from the left atrium of the heart into the left ventricle. Mitral regurgitation occurs when the mitral valve leaks blood back into the left atrium.