But cancer cells also cross established boundaries, grow into the surrounding tissue and multiply. And they can detach from the cell structure and spread via the blood or lymphatic vessels to ...

Approaches Against Metastatic Breast Cancer: Mini-Tumors from Circulating Cancer Cells Jan. 3, 2025 — Tumor cells circulating in the blood are the 'germ cells' of breast cancer metastases.

9 Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China Objective Metastasis is the major cause of cancer death. However, what types of heterogenous cancer cells ...

Mechanisms of the spread of Krukenberg tumor proposed are retrograde lymphatic dissemination involved in gastric cancer metastases, hematogenous spread most frequent in colorectal cancer, and ...

the above findings suggest that tumor stroma is far from a passive bystander during tumor metastases. Tumor cells influence stromal changes including remodeling of the ECM, and this changed stroma ...

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In this review, we summarize TAM ontogeny and polarization, and then explore how TAMs enhance tumor cell migration through the TME, thus facilitating metastasis. We also discuss how chemotherapy and ...

Bone is a common organ for solid tumor metastasis. Malignant bone tumor becomes insensitive to systemic therapy after colonization, followed by poor prognosis and high relapse rate. Immune and bone ...

Cervical cancer starts in the cells of the cervix. The cervix is the narrow passageway connecting the uterus to the vagina. Cervical cancer accounts for 1.3% of all new female cancers and 1.1% of all ...