Pheochromocytoma : Chromaffin Reaction - WebPathology
This is due to oxidation of stored catecholamines synthesized by the tumor and is known as the Chromaffin Reaction. Pheochromocytomas have the capacity to synthesize both norepinephrine and epinephrine, where as extra-adrenal paragangliomas can synthesize only norepinephrine (as they lack the enzyme phenylethanolamine-N-methyl transferase ...
Chromaffin cell - Wikipedia
Chromaffin cells, also called pheochromocytes (or phaeochromocytes), are neuroendocrine cells found mostly in the medulla of the adrenal glands in mammals. These cells serve a variety of functions such as serving as a response to stress, monitoring carbon dioxide and oxygen concentrations in the body, maintenance of respiration and the ...
PHEOCHROMOCYTOMA - Pathology Made Simple
2024年2月9日 · The chromaffin reaction involves the affinity of chromaffin cells to chromium salts, leading to the oxidation of catecholamines, which imparts a brown color to the cells under a potassium dichromate stain, aiding in the diagnosis.
Pheochromocytoma – Histopathology.guru
Chromaffin reaction. Dichromate containing fixatives may produce the chromaffin reaction on fresh tumor tissue resulting in a dark brown colour. Freshly cut tumor tissue when immersed in Potassium dichromate(pH of 5 to 6), it turns dark brown due to oxidation of stored catecholamines synthesized by tumor cells. Pheochromocytoma with malignant ...
What's New in Endocrinology: The Chromaffin Cell - PMC
Chromaffin cells themselves not only operate as individual cellular elements that amplify signal transduction by being organized into an endocrine organ, but also modulate the performance of this cellular cohort by chromaffin cell-chromaffin cell coordination through gap junctions.
Chromaffin Cell - an overview | ScienceDirect Topics
Chromaffin cells are neuroendocrine cells with oxygen-sensing properties. Chromaffin organs include the adrenal medulla and Zuckerkandl organ. Schwann cell precursors (SCPs) generate chromaffin and carotid organs. Abnormal development of SCPs or other progenitors might lead to variety of tumors.
Chromaffin Cell - SpringerLink
2022年11月25日 · Chromaffin cells are cells located in the adrenal gland and sympathetic paraganglia. The term “chromaffin” derives from their reaction with chromium salts, which depends on the oxidation of catecholamines stored in secretory granules.
Forty years of the adrenal chromaffin cell through ISCCB ...
2023年3月8日 · The term “chromaffin reaction” was applied to cells that reacted in this manner to chromium, the adrenal medulla being the prime example. The chrome reaction was found to be a reduction by adrenaline [ 147 ].
these reactions constitute a "fight or flight" response that prepares one to combat an enemy or flee from danger. They are the end result of a secretory event in the adrenal medulla: the inner part of the two adrenal glands just above the kidneys. There specialized cells known as chromaffin cells manu facture, store and secrete a complex
According to Coupland (1965, 1972) a chromaffin cell develops from neuroec toderm, is innervated by preganglionic ("sympathetic") nerve fibres, synthesizes and releases catecholamines, and stores sufficient quantities of catecholamines to give a chromaffin reaction.