One of the most common treatments for diffuse large B-cell lymphoma is R-CHOP. It combines the monoclonal antibody drug rituximab with three chemotherapy drugs and a corticosteroid. This treatment is safe and effective but doesn’t always work or …

Diffuse large B-cell lymphoma (DLBCL) tends to grow quickly. Most often, the treatment is chemotherapy (chemo), usually with 4 drugs known as CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), plus the monoclonal antibody rituximab (Rituxan).

Since DLBCL can advance quickly, it usually requires immediate treatment. A combination of chemotherapy and the monoclonal antibody rituximab (Rituxan), with or without radiation therapy, can lead to disease remission in a large number of patients with this form of lymphoma.

2024年4月15日 · Diffuse large B-cell lymphoma can progress rapidly, so prompt treatment is important. Mayo Clinic expert hematopathologists excel at providing the right diagnosis the first time. Lymphoma specialists offer innovative therapies, including CAR-T cell therapy and bone marrow transplant, as well as access to promising clinical trials.

2024年2月29日 · Chemotherapy is generally the first treatment for DLBCL, but it isn’t right for everyone for many reasons. Plus, not everyone with DLBCL responds to chemotherapy. Thanks to advances in cancer...

2024年4月23日 · Several types of third-line treatments for DLBCL are available. The treatment plan for a specific person depends on several factors, such as past therapies and overall health. When appropriate, the preferred therapies for third-line treatment are CAR-T cell therapy and bispecific antibody therapy.

2022年11月2日 · DLBCL is fatal if left untreated, but with timely and appropriate treatment, approximately two-thirds of all people can be cured. The following discussion will review the risk factors, classification, symptoms, treatment, and prognosis of this type of non-Hodgkin lymphoma. Age, gender, and ethnicity affect a person's likelihood of developing DLBCL.

2024年2月22日 · Diffuse large B-cell lymphoma (DLBCL) is a subtype of non-Hodgkin’s lymphoma. Though many people will respond to first-line treatment options, many will experience refractory or relapsed...

2020年9月29日 · As with many blood cancers, the first line treatment for DLBCL is chemotherapy. In most cases, patients receive a combination of five medications, known as R-CHOP. R-CHOP, or other more intense treatment combinations, is often successful in curing DLBCL.

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL). It is an aggressive (fast-growing), but treatable, lymphoma that starts in B cells. There are many different subtypes of DLBCL.