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    Wikipedia
    https://en.wikipedia.org › wiki › Fentanyl

    Fentanyl - Wikipedia

    • Fentanyl continues to fuel an epidemic of synthetic opioid drug overdose deaths in the United States. From 2011 to 2021, deaths from prescription opioid (natural and semi-synthetic opioids and methadone ) per year remained stable, while synthetic opioid (primarily fentanyl) deaths per year increased from 2,600 overdoses to 70,601. [ 24 ]… 展开

    Overview

    Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic. It is 30 to 50 times more potent than heroin and 50 to 100 times more potent than morphine. Its primary clinical utility is in pain management for … 展开

    Medical uses

    Intravenous fentanyl is often used for anesthesia and as an analgesic. To induce anesthesia, it is given with a sedative-hypnotic, like propofol or thiopental, and a euphoriant. To maintain anesthesia, inhaled anestheti… 展开

    Adverse effects

    Fentanyl's most common side effects, which affect more than 10% of people, include nausea, vomiting, constipation, dry mouth, somnolence, confusion, and asthenia (weakness). Less frequently, in 3–10% of people, fentanyl … 展开

    How many people die from opioid overdoses in 2021?
    In the United States in 2021, following a year-on-year trend of increase, there were more than 80,000 opioid overdose deaths. Most of those deaths, 70,000, were attributed to any pharmaceutical opioid with synthetic opioids (primarily fentanyls).
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