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  1. Management of HIV/AIDS - Wikipedia

    • The management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. There are several classes of antiretroviral agents that act on different stages of the HIV life-cycle. The use of multiple drugs that act on different viral targets is known as highly active antiretroviral therapy (HAART). HAART decreases th… 展开

    Classes of medication

    There are six classes of drugs, which are usually used in combination, to treat HIV infection. Antiretroviral (ARV) drugs a… 展开

    Combination therapy

    The life cycle of HIV can be as short as about 1.5 days from viral entry into a cell, through replication, assembly, and release of additional viruses, to infection of other cells. HIV lacks proofreading enzymes to correct errors m… 展开

    Treatment guidelines

    Antiretroviral drug treatment guidelines have changed over time. Before 1987, no antiretroviral drugs were available and treatment consisted of treating complications from opportunistic infections and malignancie… 展开

    Concerns

    There are several concerns about antiretroviral regimens that should be addressed before initiating:
    • Intolerance: The drugs can have serious side-effects which can lead to harm as well as keep patients … 展开

    Response to therapy

    Suppressing the viral load to undetectable levels (<50 copies per ml) is the primary goal of ART. This should happen by 24 weeks after starting combination therapy. Viral load monitoring is the most important predictor of resp… 展开