Dihydrotestosterone (DHT, 5α-dihydrotestosterone, 5α-DHT, androstanolone or stanolone) is an endogenous androgen sex steroid and hormone primarily involved in the growth and repair of the prostate and the penis, as well as the production of sebum and body hair composition.

Androgens (testosterone and dihydrotestosterone (DHT)) are the male sex hormones required for development of the male reproductive system and secondary sexual characteristics. 1 Testosterone can be converted to its more biologically active form, DHT, by 5α reductase, and to oestradiol by aromatase.

Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid. Androstanolone has been reported in Homo sapiens, Aeromonas veronii, and Daphnia magna with data available. View More...

5beta-Dihydrotestosterone | C19H30O2 | CID 11302 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2021年7月2日 · The biological actions of testosterone and DHT are mediated by the androgen receptor, a member of the nuclear receptor superfamily, which in response to hormone regulates gene expression in target tissues.

DHT stimulates the growth of prostate cells, leading to the enlargement of the gland and potential urinary symptoms. Testosterone, on the other hand, does not directly contribute to prostate enlargement.

We present structures of human estrogenic 17β-hydroxysteroid dehydrogenase (17β-HSD1) complexes with dehydroepiandrosterone (DHEA) and dihydrotestosterone (DHT), providing the first pictures to date of DHEA and DHT bound to a protein.

2022年12月20日 · DHT is a hormone that contributes to the development of sexual structures and characteristics in people assigned male at birth. When DHT levels are too high or too low, it can cause different issues depending on your age and stage of sexual development. What is DHT (dihydrotestosterone)?

2023年7月30日 · Androgens are endogenous steroid hormones. They contain dehydroepiandrosterone (DHEA), androstenedione, testosterone, and dihydrotestosterone (DHT). DHT is the most potent hormone among the androgens and is considered a pure androgen as it cannot convert into estrogen.

2D Structure. An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor.