In immunology, an Fc receptor is a protein found on the surface of certain cells – including, among others, B lymphocytes, follicular dendritic cells, natural killer cells, macrophages, neutrophils, eosinophils, basophils, human platelets, and mast cells – that contribute to the protective functions of the immune system.

2021年11月10日 · Fc receptors (FcRs) are a group of glycoproteins that belong to the immunoglobulin superfamily and are classified, like Fc alpha receptors (FcαRs), Fc gamma receptors (FcγRs) and Fc epsilon ...

2025年1月10日 · Fc receptors are fundamental in orchestrating immune responses, acting as conduits for communication between antibodies and immune cells. Their ability to bind antibodies allows them to translate the presence of antigens into actionable cellular processes.

Antibodies are major molecular effectors of adaptive immune responses. Most, if not all, biological activities of antibodies, however, depend on the functional properties of cells that express receptors for the Fc portion of antibodies (FcR). Most ...

Fc receptors (FcRs) belong to the ITAM-associated receptor family. FcRs control the humoral and innate immunity which are essential for appropriate responses to infections and prevention of chronic inflammation or auto-immune diseases.

2019年4月11日 · Fc receptors (FcRs) belong to the ITAM-associated receptor family. FcRs control the humoral and innate immunity which are essential for appropriate responses to infections and prevention of chronic inflammation or auto-immune diseases.

Human and mouse Fc receptors for IgG (FcγRs) can be distinguished by their affinity for the antibody Fc-fragment and by the signalling pathways they induce.

Fc receptors (FcRs) are a group of glycoproteins belonging to the immunoglobulin superfamily and are organized into classes, such as Fc alpha receptors (FcαRs), Fc gamma receptors (FcγRs) and Fc epsilon receptors (FcεRs).

Fc receptors (FcRs) are a series of cell-surface receptors that specifically recognize the Fc region of immunoglobulins. The Fc receptors are mainly expressed on phagocytic cells such as macrophages, DCs, and B lymphocytes, and consist of the Fc receptors of IgE (FcεRs), IgG (FcγRs and neonatal FcR (FcRn), IgA (FcαRs), IgM (FcμRs), and IgD ...

Similar studies on B-lymphocytes extended the generality of these receptors and led to the term Fc receptor (FcR) to denote the surface molecules on lymphoid and myeloid cells that are capable of interacting with the Fc of immunoglobulin molecules. 3 Studies on IgE, IgM, and IgA demonstrated the existence of distinct receptors for those ...