Mechanisms regulating GABAergic neuron development
2013年11月7日 · Here, we review the gene expression and regulatory mechanisms controlling the main steps of GABAergic neuron development: early patterning of the proliferative …
Microglia regulate GABAergic neurogenesis in prenatal human …
2024年10月19日 · Using our newly developed neuroimmune hMGE organoids, which mimics hMGE cytoarchitecture and developmental trajectory, we demonstrate that microglia-derived …
GABA receptors in brain development, function, and injury
Development abnormalities of the GABAergic system appear particularly relevant in the etiology of schizophrenia. This review also covers the potential role of GABA in mature brain injury, …
The diversity of GABAergic neurons and neural communication ... - Nature
2019年6月20日 · The spectacular diversity of GABAergic neurons enables an elaborate division of labour in deploying a rich repertoire of inhibitory control mechanisms to shape highly nuanced …
Mechanisms regulating GABAergic neuron development
Here, we review the gene expression and regulatory mechanisms controlling the main steps of GABAergic neuron development: early patterning of the proliferative neuroepithelium, …
Regulation of adult neurogenesis by GABAergic transmission: …
In this review, we systematically compare the role of GABAergic transmission in the regulation of adult neurogenesis between the OB and the hippocampus, focusing on the role of GABA in …
Gabaergic Interneurons in Early Brain Development: Conducting …
All GABAergic interneurons produce GABA, the hyperpolarizing action of which in the mature brain accounts for their definition as inhibitory neurons. GABAergic neurons form a …
GABAergic neurons maturation is regulated by a delicate network
2022年11月18日 · This review focuses on the current knowledge regarding the molecular mechanisms required for GABAergic neuron maturation, including the regulators of neural …
GABAergic neuron-to-glioma synapses in diffuse midline gliomas
2025年2月19日 · We sought to visualize GABAergic synapses between GABAergic neurons and DMG tumour cells. First, we expressed a construct encoding the GABA A subunit GABRG2 …
The role of GABAergic signalling in neurodevelopmental …
2021年3月26日 · In this article, we review studies that characterize developmental processes of the GABAergic inhibition system in normal brains, and recent work using preclinical models of …
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