2024年11月3日 · Lumateperone is effective in treating bipolar depression but does not significantly reduce symptom severity in schizophrenia. It has a favorable safety and tolerability profile. However, caution is warranted in interpreting these findings due to the...

2020年5月25日 · I’m taking my first capsule of Lumateperone 42 mg tonight. Steady state should be reached in 5 days. Will share my experiences here.

2016年5月10日 · ITI-007 (Lumateperone Tosylate) for Schizophrenia. News. 1: 444: January 28, 2019

2019年12月23日 · When can one buy Lumateperone in the US/Europe? Medications. 9: 1318: June 21, 2018 ...

2019年12月24日 · Will Lumateperone have less dopamine blocking than other antipsychotics? And do you think it will have less sexual side effects than other antipsychotics? Apparently it does block less dopamine then current antipsychotics… “This level of occupancy is lower than most other antipsychotic drugs at their efficacious doses and likely contributes to the favorable …

2019年6月27日 · Lumateperone is a potent 5-HT2A antagonist, a mesolimbic/mesocortical dopamine phosphoprotein modulator (DPPM) with pre-synaptic partial agonist and post-synaptic antagonist activity at D2, a glutamate GluN2B receptor phosphoprotein modulator with D1-dependent enhancement of both NMDA and AMPA currents via the mTOR protein pathway …

2016年5月10日 · Lumateperone (ITI-722) is a low-dose formulation of ITI-007 (ITI’s first-in-class 5-HT2A antagonist/ dopamine receptor protein phosphorylation modulator (DPPM), presently in clinical trials for the treatment of schizophrenia) Lumateperone (ITI-722) is a highly potent 5HT2A antagonist for the treatment of sleep maintenance insomnia.

2020年11月1日 · When can one buy Lumateperone in the US/Europe? Medications. 9: 1318: June 21, 2018 Lumateperone.

2021年6月7日 · Lumateperone (lumateperone tosylate, ITI-007) is a mechanistically novel investigational agent for schizophrenia.9 The mechanism of action of lumateperone is unique because it simultaneously modulates serotonin, dopamine, and glutamate neurotransmission, the key neurotransmitters implicated in serious mental illness.9 Specifically, lumateperone ...

2017年1月24日 · Hey guys, this is my first post, I joined about a few days ago and I will be hoping to post more these coming months. Anyway, I’m still trying to find a medication that works, but I have heard a bit about Lumateperone, a drug that seems to lack significant side effects and is very effective at lessening negative symptoms (negative symptoms being one of my primary …