most frequent constitutional translocation in humans, the t (11;22 ...
2000年6月12日 · The t(11;22) is the most common recurrent non-Robertsonian constitutional translocation in humans, having been reported in more than 160 unrelated families. Balanced …
The 11/22 Translocation - Emanuel Syndrome
A reciprocal translocation means that there is a two-way exchange of information between these two chromosomes. Nothing is missing and nothing is extra, thus making a carrier of this …
In people with the 11;22 translocation, the bottom bit of one chromosome 11 (a medium-sized chromosome) has transferred to chromosome 22 (a small chromosome) and the bottom bit of …
Reciprocal Chromosome Translocation - an overview
Reciprocal chromosome translocations are defined as the reciprocal exchange of genetic material between two chromosomes, with a break point in each of them. This exchange can be …
Site-specific reciprocal translocation, t(11;22) (q23;q11), in …
We have studied 32 unrelated families with a site-specific reciprocal translocation between chromosomes 11 and 22 [t (11;22) (q23;q11)]. In translocation heterozygotes 3:1 meiotic …
AT-Rich Palindromes Mediate the Constitutional t(11;22) Translocation
The LCR22s contain AT-rich repetitive sequences, suggesting that such repeats may mediate the t(11;22) translocation. To determine the molecular basis of the translocation, we cloned and …
chromosome 22 in band qll are numerous and found to be (1), which involves the same chromosomal regions. The associated with a diversity of neoplasms as well as constitutional …
Precise location of breakpoints in a frequent reciprocal translocation ...
One of the most frequent chromosomal translocations in human beings is 11q/22q, which results in the "partial trisomy of 22q syndrome." However, the breakpoint on the long arms of …
A Common Breakpoint on 11q23 in Carriers of the Constitutional t(11;22 …
1999年11月18日 · To determine the molecular basis of the reciprocal t (11;22) translocation in the normal carrier parents, it is necessary to characterize the breakpoint intervals on 11q23 and …
Comparison of constitutional and tumor-associated 11;22 translocations ...
Chromosome 11 in bands q23-q24 is similarly involved in several types of tumors as well as in a recurring constitutional reciprocal translocation with chromosome 22. Here we report the use …