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[Treg/Th17 balance and immunology of schistosome infection: a …
2018年10月17日 · Many factors are reported to be involved in regulating the immunopathogenesis of schistosome infection. CD4 + T cell is one of the key players in the …
Functional Studies of T Regulatory Lymphocytes in Human Schistosomiasis …
Immunoregulation is considered a common feature of Schistosoma mansoni infections, and elevated levels of T regulatory (Treg) lymphocytes have been reported during chronic human …
Regulatory and Activated T Cells in Human Schistosoma ... - PLOS
2011年2月10日 · This study investigated the relationship between schistosome infection intensity and the two cell populations regulatory T cells (Treg: …
CD4+CD25hiFOXP3+ Regulatory T Cells and Cytokine Responses …
Here we provide evidence that human Schistosoma infection is associated with increased FOXP3 + regulatory T cells that play a significant role in controlling Th1 and Th2 responses. This …
Excessive immunosuppression by regulatory T cells antagonizes T …
2022年6月6日 · Schistosomiasis is caused by parasitic flatworms known as schistosomes and affects over 200 million people worldwide. Prevention of T cell exhaustion by blockade of PD-1 …
T Regulatory Cell Levels Decrease in People Infected With Schistosoma …
Experimental Schistosoma mansoni infection is associated with immunoregulatory mechanisms, including T regulatory cells (Treg) that may help control morbidity and dampen resistance to re …
Functional Studies of T Regulatory Lymphocytes in Human Schistosomiasis ...
Immunoregulation is considered a common feature of <i>Schistosoma mansoni</i> infections, and elevated levels of T regulatory (Treg) lymphocytes have been reported during chronic …
Schistosome immunomodulators | PLOS Pathogens
2021年12月30日 · The hallmark of the immune response toward schistosomes is the induction of a Th2 response in both humans and mice [2,4,8–11] and by the generation of regulatory T …
Schistosoma japonicum Infection in Treg-Specific USP21 …
2021年2月9日 · Our results revealed the roles of USP21 in Treg-cell-mediated regulation of immune interactions between Schistosoma and its host. USP21 may have potential for …
Treg/Th17平衡与血吸虫感染免疫
摘要: 血吸虫感染可诱导调节性T细胞(Treg)和Th17型免疫反应。研究表明,Treg和Th17细胞及其平衡在血吸虫感染中具有非常重要的作用。Treg细胞抑制宿主体内过度病理反应,并有助 …