Linking single-cell transcriptomes with secretion using SEC-seq
15 小时之前 · To link the amount of secretion of a target protein from a cell with the same cell’s transcriptome, we have developed secretion encoded single-cell sequencing (SEC-seq) 3,4,5. …
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Combining T cell receptor sequencing and transcriptomics to ...
4 天之前 · In this proof-of-concept study, we established and validated methods to perform bulk and single cell TCR and RNA sequencing of T cells isolated from human gut biopsies of the …
What is the main bottleneck in deriving biological ... - Cell Press
1 天前 · Image-based approaches to single-cell transcriptomics offer the exciting ability to directly image gene expression at the transcriptome scale within intact tissue slices, defining, …
Transcriptome and Functional Comparison of Primary and ... - MDPI
1 天前 · To compare the determined transcriptome data of the three cell types, ... so that even rare transcripts are detected at a 10- to 20-fold lower sequencing depth compared to …
Cell Discovery|Droplet-based high-throughput 3D genome …
1 天前 · The researchers also demonstrated that dscHi-C is robust, sensitive, and scalable for applications in cell lines and tissues. The advancement of single-cell 3D genome technologies, …
A large-scale integrated transcriptomic atlas for soybean organ ...
2 天之前 · The emergence of omics, particularly the integration of previously well-493 established bulk RNA-seq with recently developed single-cell transcriptome 494 J ur al Pre- pro of 19 …
Single‐cell transcriptomic atlas of different endometriosis …
1 天前 · Mesothelial cells have also been reported in previous single-cell transcriptome sequencing articles on endometriosis. 14, 17 Previous study reported that mesothelium in …
Single-cell transcriptomics reveals inter-ethnic variation in immune ...
2 天之前 · Comparative analysis of the single-cell transcriptomic profiles of peripheral blood immune cells from Fulani and Mossi ethnic groups in Burkina Faso revealed a significant …
Comparative models of uveitis | Eye - Nature
2 天之前 · More recently, single-cell RNA sequencing (scRNA-seq) has provided high-resolution transcriptomic data, revealing cell heterogeneity and therefore rarer subsets in disease …
Single-cell RNA sequencing identifies molecular biomarkers …
5 天之前 · Background Cyclin-dependent kinase 4/6 inhibitors (CDK4/6is) in combination with endocrine therapy are the standard treatment for patients with hormone receptor–positive, …