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    https://en.wikipedia.org › wiki › Clomipramine

    Clomipramine - Wikipedia

    • Studies have found that high dosages of SSRIs above the normally recommended maximums are significantly more effective in OCD treatment than lower dosages (e.g., 250 to 400 mg/day sertraline versus 200 mg/day sertraline). 展开

    Overview

    Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). It is used in the … 展开

    Medical uses

    Clomipramine has a number of uses in medicine, including in the treatment of:
    • Obsessive–compulsive disorder (OCD), which happens to be its only US FDATooltip Food and Drug Administration-labeled indication. Other … 展开

    Contraindications

    Contraindications include:
    • Known hypersensitivity to clomipramine, or any of the excipients or cross-sensitivity to tricyclic antidepressants of the dibenzazepine group
    • Recent myocardial infarction… 展开

    Side effects

    Clomipramine has been associated with the side effects listed below:
    Very common (>10% frequency):
    • Accommodation defect
    • Blurred vision
    • Nausea… 展开

    Withdrawal

    Withdrawal symptoms may occur during gradual or particularly abrupt withdrawal of tricyclic antidepressant drugs. Possible symptoms include: nausea, vomiting, abdominal pain, diarrhea, insomnia, headache, nervo… 展开

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    Overview
    Medical uses
    Contraindications
    Side effects
    Withdrawal