In molecular biology, SUMO (S mall U biquitin-like Mo difier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their …

SUMOylation involves the covalent attachment of a member of the SUMO (small ubiquitin-like modifier) family of proteins to lysine residues in specific target proteins via an enzymatic …

2024年1月27日 · SUMOylation, which is a type of post-translational modification that involves covalent conjugation of small ubiquitin-like modifier (SUMO) proteins to target substrates, …

SUMOylation is the attachment of approximately 100 amino acids of small ubiquitin-like modifier (SUMO) to lysine residues [125]. SUMOylation alters the regulation of transcription, cell cycle, …

Sumoylation alters the molecular interactions of modified target proteins by masking or adding interaction surfaces. Downstream consequences, which are target dependent,...

Discover the intricate world of SUMOylation: mechanisms, biological roles, and implications in cancer pathways. Explore the catalytic cycle and detection methods. Learn how SUMOylation …

2022年6月24日 · Sumoylation is an essential post-translational modification that is catalysed by a small number of modifying enzymes but regulates thousands of target proteins in a...

Sumoylation is an essential post-translational modification that has evolved to regulate intricate networks within emerging complexities of eukaryotic cells. Thousands of target substrates are …

SUMOylation is a mechanism of protein modification by the addition or deletion of small ubiquitin-like modifier (SUMO) proteins, a complex of highly conserved ∼90 amino acids (Wang et al., …

2020年4月7日 · Sumoylation is an essential post-translational modification intimately involved in a diverse range of eukaryotic cellular mechanisms. Small ubiquitin-like modifier (SUMO) protein …