2016年12月1日 · The wet granulation process plays an important role in extrusion–spheronization. With the introduction of a twin screw extruder (TSE), it allows the possibility of wet granulation to run continuously in contrast to a conventional batch process using a high shear mixer (HSM).

2022年1月1日 · In order to avoid the energy consumption of dewatering and dust pollution in the preparation of non-sintered lightweight aggregates from dredged sediment, a new low-dust process of preparing non-sintered extruded wrap-shell aggregates (TH-WSLAs-W) by extrusion granulation is proposed and applied to produce TH-WSLAs-W baking-free bricks (TH ...

2015年5月1日 · Twin screw extrusion (TSE) is a continuous process widely used in the food, polymer and chemical processing industries for compounding and extruding. Over the last decade or so the use of twin screw extruders for granulation has attracted considerable and serious interest in the pharmaceutical industry.

Granulation, the process of particle enlargement by agglomeration technique, is one of the most significant unit operations in the production of pharmaceutical dosage forms, mostly tablets and capsules. Granulation process transforms fine powders into free-flowing, dust-free granules that are easy to compress.

2005年1月1日 · Extrusion/spheronization is a multiple step process capable of making uniformly sized spherical particles. The process is now being widely utilized in the pharmaceutical industry. This...

Extrusion spheronization is a process in pharmaceutical manufacturing to create spherical pellets for controlled -release formulations. It involves the use of Active Pharmaceutical Ingredient (API), excipients like binders, fillers, lubricants, disintegrants, plasticizers, and

2024年5月24日 · Twin-screw granulation has emerged as a key process in powder processing industries and in the pharmaceutical sector to produce granules with controlled properties. This comprehensive review provides an overview of the simulation techniques and approaches that have been employed in the study of twin-screw granulation processes.

2021年12月14日 · Granulation technique can be effortlessly converted into a continuous phase using extrusion technology that involves two screws revolving within a barrel to constantly convey, blend, and agglomerate wet particles, where the energy required for material densification is provided by shear and/or heating.

2024年2月1日 · Granulation is an essential process for the industrial application of adsorbents packed in adsorption towers, given the high bed pressure drop and powder loss. In this study, a novel extrusion granulation method together with an antisolvent strategy was developed for the aluminum-based lithium adsorbent powder, which has been successfully ...

2025年2月25日 · One crucial component for their production is the thermal processing of high-quality plastic granulates with defined grain sizes. These granulates are generated through targeted and repeatedly accurate mechanical granulation of hard copolymer panels.