Compare Fluconazole vs Micafungin head-to-head with other drugs for uses, ratings, cost, side effects and interactions.

2024年8月3日 · Fluconazole may be used as initial therapy for mild infection (e.g., candida esophagitis). Fluconazole shouldn't be used as empiric therapy for invasive Candida infection acquired in the ICU. However, fluconazole may be used as a step-down therapy, following empiric treatment with an echinocandin (if the Candida species is sensitive to ...

2009年9月1日 · Initial therapy for most nonneutropenic adults with candidemia should be fluconazole (Diflucan) or an echinocandin (e.g., caspofungin [Cancidas], anidulafungin [Eraxis], micafungin...

2005年4月1日 · Intravenous micafungin (150 mg daily) is well tolerated and as efficacious as intravenous fluconazole (200 mg daily) in the primary treatment of oesophageal candidiasis, achieving high rates of clinical and endoscopic cure.

2015年12月16日 · Alternatives for fluconazole-refractory disease include an echinocandin (micafungin: 150 mg daily; caspofungin: 70-mg loading dose, then 50 mg daily; or anidulafungin: 200 mg daily) for 14–21 days, OR AmB deoxycholate, 0.3–0.7 mg/kg daily, for 21 days (strong recommendation; high-quality evidence).

(1) 首選治療：Echinocandin，例如Caspofungin、Micafungin、Anidulafungin等。 (2) 替代選擇：Fluconazole，但IDSA建議用於＂特定族群＂病人，例如對 Fluconazole 可能＂沒有抗藥性＂的病人。 (3) 一旦臨床狀況穩定 (通常是開始用藥後5～7天)、培養出的念珠菌對 Fluconazole 具有敏感性，且在開始使用抗黴菌藥品後血液培養陰性，可以考慮從 Echinocandin 轉為 Fluconazole。

2008年11月29日 · To test this hypothesis, we conducted a randomized, open-labeled, multicenter, clinical trial that compared the efficacy of micafungin treatment (150 mg) with fluconazole (400 mg) for the prevention of invasive fungal infections during the neutropenic phase of …

2004年11月15日 · We hypothesized that chemoprophylaxis with the echinocandin micafungin would be an effective agent for antifungal prophylaxis during neutropenia in patients undergoing hematopoietic stem cell transplantation (HSCT). We therefore conducted a randomized, double-blind, multi-institutional, comparative …

2015年12月3日 · Here, we evaluated and compared the incidence rate of proven or probable invasive fungal infections (IFIs) with antifungal prophylaxis using micafungin or fluconazole. Methods: This is a prospective, single center, phase II study involving adult patients who received allogeneic or autologous HSCT.