The cryo-EM at Pfizer’s Groton site is a hulking structure about the size of a large van that sits in a darkened, temperature-controlled room. Once a sample is loaded into the microscope, the machine can operate autonomously for a few days, spitting out image files that are 2 to 3 terabytes in size — the equivalent of thousands of high ...

Thanks to a recent strategic research collaboration with XtalPi, a U.S.-China pharmaceutical tech company, Pfizer scientists are performing crystal structure prediction in a matter of days. Pioneered by a group of quantum physicists from MIT, the XtalPi technology leverages artificial intelligence and cloud computing to perform these complex ...

2012年12月14日 · To protect its brand and maintain its high-quality reputation, Pfizer turned to METTLER-TOLEDO Safeline to address these quality-control issues, and the solution came in the form of a PowerChek* x-ray inspection system which, as well as detecting and rejecting multiple foreign bodies, can simultaneously verify product and packaging integrity.

Georgetown University's prototype of the ACTA scanner caught the attention of the pharmaceutical giant Pfizer, which acquired the rights to manufacture it. Pfizer subsequently introduced their version of the machine, called the "200FS" (with "FS" denoting Fast Scan).

Pfizer Installs X-Ray Inspection Technology For Quality Assurance of OTC Blister Packaged Products Source: Mettler-Toledo Product Inspection Pfizer Pharmaceuticals LLC, the largest drug manufacturer in the world, produces both prescription and over-the-counter drugs.

2020年7月2日 · However, for the vast majority of projects at Pfizer, X-ray crystallography was engaged after a fragment hit was identified and confirmed by NMR as described above.

2021年12月22日 · Scientists at Pfizer created Paxlovid with the help of the ultrabright X-rays of the Advanced Photon Source (APS), a U.S. Department of Energy (DOE) Office of Science user facility at DOE ’s Argonne National Laboratory.

2012年1月1日 · Powder X-ray diffraction is ideally suited to monitor the development of crystallinity as well as changes in crystalline forms. In this paper, we describe different methods for powder X-ray diffractometry of a monoclonal antibody formulation, a DNA delivery system, and a vaccine formulation. Materials and Methods

The patient was essentially inside a large x-ray tube that had a 6’ semicircular anode and an electron beam that was electronically scanned in 33 to 100 ms over one of four anode tracks to produce a focal spot that rotated 210 deg.

Joined by our clients from Pfizer, we are proud to share the first paper employing non-invasive 3D imaging and AI-based image analytics to characterize semi-solid pharmaceutical products ...