
Role of pyroptosis in atherosclerosis and its therapeutic
Atherosclerosis is a significant cardiovascular burden and a leading cause of death worldwide, recognized as a chronic sterile inflammatory disease. Pyroptosis is a novel proinflammatory …
GSDME-mediated pyroptosis promotes the progression and
2023年2月18日 · Pyroptosis, a type of Gasdermin-mediated cell death, contributes to an exacerbation of inflammation. To test the hypothesis that GSDME-mediated pyroptosis …
Roles of pyroptosis in atherosclerosis pathogenesis
2023年10月1日 · Pyroptosis is a pro-inflammatory type of regulated cell death (RCD) characterized by gasdermin protein-mediated membrane pore formation, cell swelling, and …
Pyroptosis and its relationship to atherosclerosis - PubMed
Pyroptosis is a pro-inflammatory form of regulated cell death and is dependent on the enzymatic activity of inflammatory proteases that belong to the family of cysteine-dependent aspartate …
The Molecular Pathways of Pyroptosis in Atherosclerosis
Pyroptosis is a newly discovered pattern of programmed cellular necrosis (Bin He et al., 2021), characterized by cell swelling, plasma membrane rupture, and massive production and release …
Role of pyroptosis in atherosclerosis and its therapeutic …
Atherosclerosis is a significant cardiovascular burden and a leading cause of death worldwide, recognized as a chronic sterile inflammatory disease. Pyroptosis is a novel proinflammatory …
Pyroptosis in the Initiation and Progression of Atherosclerosis
2021年5月25日 · Here, we provide an overview of the role of pyroptosis in atherosclerosis by focusing on three important participating cells: ECs, macrophages, and SMCs. In addition, we …
GSDMD-mediated pyroptosis: molecular mechanisms, diseases …
Pyroptosis is a regulated form of inflammatory cell death in which Gasdermin D (GSDMD) plays a central role as the key effector molecule. ... Atherosclerosis, characterized as an inflammatory …
Roles of pyroptosis in atherosclerosis pathogenesis - PubMed
Pyroptosis is a pro-inflammatory type of regulated cell death (RCD) characterized by gasdermin protein-mediated membrane pore formation, cell swelling, and rapid lysis. Recent studies have …
GSDMD-mediated pyroptosis: molecular mechanisms, diseases …
2025年2月25日 · Pyroptosis is a regulated form of inflammatory cell death in which Gasdermin D (GSDMD) plays a central role as the key effector molecule. GSDMD-mediated pyroptosis is …