2021年1月20日 · Thyroglobulin is a protein used to make thyroid hormones. Doctors mainly check its levels to determine if thyroid cancer has returned after surgery and radiation. Thyroglobulin antibodies may point to autoimmune thyroid diseases such as Hashimoto’s and Graves’ disease.

2022年9月8日 · What is a thyroglobulin test? A thyroglobulin test measures the level of thyroglobulin in a sample of your blood. Thyroglobulin is a protein that your thyroid makes. Your thyroid is a small, butterfly-shaped gland in your neck.

Thyroglobulin (Tg) is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Tg is secreted and accumulated at hundreds of grams per litre in the extracellular compartment of the thyroid follicles, accounting for approximately half of the protein content of the thyroid gland. [5]

Thyroglobulin (Tg) is a thyroid-specific glycoprotein (approximately 660 kDa) that serves as the source for thyroxine (T4) and triiodothyronine (T3) production within the lumen of thyroid follicles. For T4 and T3 release, Tg is reabsorbed into thyrocytes and proteolytically degraded, liberating T4 and T3 for secretion.

2021年12月20日 · Thyroglobulin is a protein that is produced by the thyroid gland. This helps in the synthesis of the thyroxine and the triiodothyronine. Thyroglobulin plays a significant role in storing iodine and thyroid hormones in the inactive form. Thyroglobulin concentration in the blood of healthy individuals is usually very low.

Thyroglobulin is made by normal thyroid cells, and made by most thyroid cancer cells. For example, for patients with papillary or follicular thyroid cancer, nearly all cancer cells make thyroglobulin. Patients with medullary or anaplastic thyroid cancer will not make any thyroglobulin.

2023年6月1日 · Small amounts of thyroglobulin are normal in those with normal thyroid function. Thyroglobulin levels should be undetectable or very low after a thyroidectomy (surgical removal of the thyroid) and/or after subsequent radioactive iodine treatments.

Thyroglobulin testing is primarily used as a tumor marker to evaluate the effectiveness of treatment for differentiated thyroid cancer and to monitor for recurrence. The reference range of...

2022年11月24日 · Thyroglobulin (Tg) is a protein made by the thyroid gland. Certain types of thyroid cancer can also produce Tg. The Tg test is a type of tumor marker test used to measure the amount of Tg in the blood.

2019年8月6日 · Thyroglobulin is a protein produced by follicle cells and stored in the thyroid gland. Thyroglobulin is broken down to release the thyroid hormones T4 (thyroxine) and T3 (triidothyronine) when needed. The production of these hormones and their release into the blood stream is stimulated by the hormone TSH (thyroid stimulating hormone).