Proposition 65 warnings advise of exposures to chemicals that may contribute to an individual's overall lifetime risk of cancer or risk of birth defects or other reproductive harm.

2025年1月17日 · Proposition 65, officially known as the Safe Drinking Water and Toxic Enforcement Act of 1986, was enacted as a ballot initiative in November 1986. The proposition …

Proposition 65 requires the State of California to maintain and update a list of chemicals that can cause cancer, birth defects or other reproductive harm. Businesses that expose individuals to …

您可点击此处下载NF-κB p65 (RELA)靶点介绍及实验小贴士pdf文件。 图一：NF-κB p65靶点蛋白结构。 图片来源：SWISS-MODEL。 WB实验贴士. NF-κB是一种多效性转录因子，几乎存在 …

The Safe Drinking Water and Toxic Enforcement Act of 1986 (Health and Safety Code section 25249.5 et seq.), also known as Proposition 65, requires that the Governor revise and …

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NF-κB 蛋白通常会由 p65 和 p50 形成同源/异源二聚体，在胞质中因与抑制蛋白 IkB 结合形成了三聚体复合物而处于失活状态。 当上游信号因子TNF结合到细胞膜表面受体后，受体构象改变 …

2023年2月16日 · p65是NF-κB家族的一个亚基，其存在可以激活NF-κB通路，导致其转录活性上升，进而调控细胞内多个信号通路和炎症反应。 pp65是p65的一种磷酸化修饰形式，磷酸化状态 …

Phospho-NF-kappaB p65 (Ser536) (93H1) Rabbit mAb detects NF-κB p65 only when phosphorylated at Ser536. It does not cross-react with the p50 subunit or other related …

2025年2月3日 · 要补，p65的蛋白量不能说明问题，除非你做得是核质分离，检测胞质和细胞核的p65含量，total一般是不会变的。 而p65的磷酸化才是NF-kB激活的证据，调控p65的入核. 关 …