ARF6 - Wikipedia
ADP-ribosylation factor 6 (ARF6) is a member of the ADP ribosylation factor family of GTP-binding proteins. ARF6 has a variety of cellular functions that are frequently involved in …
ARF6 Gene - GeneCards | ARF6 Protein | ARF6 Antibody
2024年12月24日 · ARF6 (ADP Ribosylation Factor 6) is a Protein Coding gene. Diseases associated with ARF6 include Cholera and Fetal Akinesia Deformation Sequence 4. Among its …
ARF6重组蛋白：细胞膜重塑中的作用—艾普蒂生物 - 知乎
ARF6（ADP-Ribosylation Factor 6）是小GTPase家族中的一员，主要参与调控细胞膜的重塑和囊泡运输。ARF6在 细胞内膜系统 的功能调节和细胞信号转导中扮演着重要角色。本文旨在探 …
Arf6 as a therapeutic target: Structure, mechanism, and inhibitors
2023年10月1日 · ADP-ribosylation factor 6 (Arf6), a small G-protein of the Ras superfamily, plays pivotal roles in multiple cellular events, including exocytosis, endocytosis, actin remodeling, …
ARF proteins: roles in membrane traffic and beyond
2006年5月1日 · ARF6 localizes to the plasma membrane and endosomal compartments, in which it regulates clathrin-dependent endocytic membrane trafficking, as well as the trafficking and...
重磅综述：Arf6在耐药性癌症治疗中发挥重要作用 - 癌症研究专区
2023年10月18日 · Arf6被认为是癌症治疗的潜在靶点。Arf6的激活受多种GEF的调节，包括细胞粘附素、EFA6和BRAG家族。最初发现Arf6调节肿瘤细胞中的细胞运动和侵袭/转移 ...
Multiple Roles for Arf6: Sorting, Structuring, and Signaling at …
Arf6 influences membrane trafficking and the actin cytoskeleton at the plasma membrane (PM). The goal of this review is to summarize these recent findings and provide a cellular context for …
Arf6 作为治疗靶点：结构、机制和抑制剂,Acta Pharmaceutica …
Arf6 regulates the progression of cancer through the activation of cell motility and invasion. Aberrant Arf6 activation is a potential therapeutic target. This review aims to understand the …
The Small GTPase Arf6: An Overview of Its Mechanisms of Action …
2019年5月5日 · The small GTase Arf6 has several important functions in intracellular vesicular trafficking and regulates the recycling of different types of cargo internalized via clathrin …
Arf6 Regulates Endocytosis and Angiogenesis by Promoting …
2023年2月22日 · ADP ribosylation factor 6 (Arf6) is a small GTPase that promotes the assembly of actin necessary for CME. In its absence, growth factor signaling is greatly diminished, which …