2024年10月10日 · Most people exposed to Acanthamoeba won't get sick. For others, it can cause serious infections of the brain, skin, eyes, and sinuses. Acanthamoeba can infect parts of the body through cuts or skin wounds or from being inhaled into the lungs or nostrils. It can get into the eyes through contact lens use.

Despite low occurrence worldwide, the mortality rate of Acanthamoeba spp. infections is very high. The pathogenesis of acanthamoebiasis is not fully understood. Acanthamoeba spp. may invade through different ways, such as the respiratory tract or breaks in the skin, resulting in hematogenous dissemination to the brain [6].

2024年10月10日 · Acanthamoeba can cause rare but very serious infections, especially in people with weakened immune systems. Nasal or sinus rinsing with unsafe water might increase the risk of an Acanthamoeba infection. See a healthcare provider if you have symptoms of an Acanthamoeba infection.

2025年1月6日 · Although non-keratitis Acanthamoeba infections are often fatal, there have been some survivors. Patients with granulomatous amebic encephalitis (GAE), an infection of the brain, have a lower chance of survival compared to those with cutaneous acanthamoebiasis, a …

Acanthamoeba is a genus of amoebae that are commonly recovered from soil, fresh water, and other habitats. The genus Acanthamoeba has two stages in its life cycle, the metabolically active trophozoite stage and a dormant, stress-resistant cyst stage. In nature, Acanthamoeba species are generally free-living bacterivores. However, they are also ...

Acanthamoeba is free-living amoebae widely distributed in the environment. The routes of entry include a break in the skin or by inhalation of windblown cyst leading to amoebae invasion of the CNS through hematogenous spread. The involvement of the CNS can result in fatal consequences within days or weeks.

Acanthamoeba is an etiological agent of keratitis and encephalitis diagnosed in human. Acanthamoeba keratitis occurs in healthy persons and may lead to visual impairment and blindness, because corneal infection with this parasite fails to induce cell-mediated immune response due to the absence of resident antigen-presenting cells in the cornea.

棘阿米巴角膜炎是严重的致盲性眼病，其主要临床特点为眼部剧烈疼痛和环形 角膜基质炎 、角膜放射状神经炎。 角膜轻度受损和局部抵抗力降低如 皮质类固醇激素 的不适当使用使棘阿米巴病原体易于侵入角膜而致病。 感染性角膜炎是严重危害视力的常见病，致病微生物常为细菌、病毒、真菌，偶为衣原体、螺旋体、寄生虫等。 明确病因，及时针对病因治疗是控制感染、维护挽救视力的关键。 棘阿米巴是小的可致病的自由生活原虫，有滋养体、包囊两个时相。 滋养体普遍栖息 …

Acanthamoeba infection is a rare but serious condition caused by a microscopic organism called Acanthamoeba. This infection primarily affects the eyes, skin, or central nervous system. Acanthamoeba can lead to severe health issues and complications, especially in individuals with weakened immune systems.

Free-living amebae belonging to the genus Acanthamoeba are the causative agents of granulomatous amebic encephalitis (GAE), a fatal disease of the central nervous system (CNS), and amebic keratitis (AK), a painful sight-threatening disease of the eyes (95, 210, 286, 325).