What Is the Purpose of an Aldolase Test? - WebMD
2023年5月25日 · Find out what you need to know about the aldolase test: how it is performed, normal values, and what it means if your aldolase level is high.
The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA
2023年9月13日 · In this study, we define a direct role for the glycolytic Aldolase A (ALDOA) protein in DNA double-strand break (DSB) repair. ALDOA is a fructose biphosphate Aldolase that catalyses...
Aldolase is a sensor for both low and high glucose, linking to
2020年12月21日 · Since aldolase possesses bidirectional activity (Fig. 1a), the ability of the ALDOA-D34S mutant to maintain mTORC1 activity might also be attributed to its ability to bind DHAP in low glucose ...
ALDOA Gene - GeneCards | ALDOA Protein | ALDOA Antibody
2024年10月1日 · ALDOA (Aldolase, Fructose-Bisphosphate A) is a Protein Coding gene. Diseases associated with ALDOA include Glycogen Storage Disease Xii and Glycogen Storage Disease Of Heart, Lethal Congenital. Among its related pathways are glycolysis (BioCyc) and Response to elevated platelet cytosolic Ca2+.
Aldolase A - an overview | ScienceDirect Topics
Aldolase is one of the principal glycolytic enzymes that catalyze the conversion of d-fructose-1,6-diphosphate to dihydroxyacetone phosphate and d-glyceraldehyde-3-phosphate. There are three cytosolic isoenzymes: aldolase A, which predominates in muscle; …
ALDOA aldolase, fructose-bisphosphate A [ Homo sapiens …
2024年11月12日 · Title: Aldolase A promotes cervical cancer cell radioresistance by regulating the glycolysis and DNA damage after irradiation. Correlations of ALD, Keap-1, and FoxO4 expression with traditional tumor markers and clinicopathological characteristics in …
Aldolase A deficiency: Report of new cases and literature review
2021年2月23日 · In this report we describe, clinical, laboratory and genetic data of two novel unrelated patients harboring mutations in the ALDOA gene who presented with episodic rhabdomyolysis, we review all previously published cases and discuss the most valuable features for diagnosis of this rare disorder.
226 - Gene ResultALDOA aldolase, fructose-bisphosphate A
2024年11月12日 · Aldolase A promotes lung cancer metastasis via PHD-mediated stabilization of HIF-1alpha and the subsequent activation of MMP9. Findings show that ALDOA expression is up-regulated in colorectal cancer (CRC) and is a hypoxia-inducible prognostic factor that is closely related to CRC malignancy.
Targeting a moonlighting function of aldolase induces
2019年9月26日 · Muscle fructose-1,6-bisphosphate aldolase (ALDOA) is among the most abundant glycolytic enzymes in all cancer cells. Here, we show that the enzyme plays a previously unknown and...
Entry - *103850 - ALDOLASE A, FRUCTOSE-BISPHOSPHATE; …
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The enzyme is a tetramer of identical 40-kD subunits.
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