AMFR Gene - GeneCards | AMFR Protein | AMFR Antibody
2024年12月24日 · AMFR (Autocrine Motility Factor Receptor) is a Protein Coding gene. Diseases associated with AMFR include Spastic Paraplegia 89, Autosomal Recessive and Transitional …
自分泌运动因子受体（AMFR）基因 | MCE - MCE-生物活性 ...
该基因座编码糖基化跨膜受体。 其配体自分泌运动因子是肿瘤细胞分泌的肿瘤运动刺激蛋白。 编码的受体也是 E3 泛素连接酶蛋白家族的成员。 它催化特定蛋白质的泛素化和内质网相关降解 …
泛素连接酶表 | Cell Signaling Technology
AMFR 是一种必不可少的内质网膜蛋白，在内质网相关降解 (ERAD) 中发挥作用。 AMFR 被发现通过泛素化转移抑制因子 KAI1 来促进肿瘤转移。 后期促进复合体/细胞周期体 (APC/C) 是一 …
AMFR - Wikipedia
Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine …
Ubiquitination regulates ER-phagy and remodelling of ... - Nature
2023年5月24日 · We found that the E3 ligase AMFR, within multimeric ER-phagy receptor clusters, catalyses FAM134B ubiquitination and regulates the dynamic flux of ER-phagy. Our …
Frontiers | Gp78 E3 Ubiquitin Ligase: Essential Functions and ...
2017年8月24日 · Autocrine motility factor receptor (AMFR), when binds with its ligand autocrine motility factor (AMF), induces a signaling cascade to mediate cancer cell motility and …
AMFR autocrine motility factor receptor [ (human)]
2025年2月8日 · Data show that autocrine motility factor receptor (AMFR) and NOTCH1 protein are the direct target genes of microRNA miR-139-5p in colorectal cancer (CRC). gp78 …
AMFR drives allergic asthma development by promoting alveolar …
2022年5月2日 · Here, we report that autocrine motility factor receptor (AMFR), an endoplasmic reticulum-resident E3 ubiquitin ligase, is upregulated in AMs of asthma and is critical for this …
The chemokine CCL1 triggers an AMFR-SPRY1 pathway that
2021年9月14日 · Mechanistically, CCL1 binding triggered ubiquitination of the ERK inhibitor Spry1 by AMFR, thus activating Ras-mediated profibrotic protein synthesis. Antibody blockade of …
Entry - *603243 - AUTOCRINE MOTILITY FACTOR RECEPTOR; AMFR …
AMFR was initially described as a 78-kD internalizing cell surface receptor for autocrine motility factor (AMF; 172400), a protein secreted by tumor cells that stimulates tumor motility …