ARMC5 Gene - GeneCards | ARMC5 Protein | ARMC5 Antibody
2025年3月30日 · ARMC5 (Armadillo Repeat Containing 5) is a Protein Coding gene. Diseases associated with ARMC5 include Acth-Independent Macronodular Adrenal Hyperplasia 2 and …
ARMC5 armadillo repeat containing 5 [ (human)] - National …
2025年2月9日 · ARMC5 mutations are frequent in cortisol-secreting primary bilateral macronodular adrenal hyperplasia and seem to be associated with a particular pattern of the …
ARMC5 Mutations in Macronodular Adrenal Hyperplasia with Cushing…
2013年11月28日 · ARMC5 inactivation decreased steroidogenesis in vitro, and its overexpression altered cell survival. Some cases of corticotropin-independent macronodular adrenal …
ARMC5 gene - MedlinePlus
The ARMC5 gene provides instructions for making a protein about which little is known. It is found mainly in the fluid surrounding the cell nucleus (cytoplasm), and studies suggest that its …
ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in ...
2022年6月24日 · ARMC5 is implicated in several pathological conditions, but its function remains unknown. We have previously identified CUL3 and RPB1 (the largest subunit of RNA …
Entry - *615549 - ARMADILLO REPEAT-CONTAINING PROTEIN 5; ARMC5 …
2022年6月28日 · Assie et al. (2013) stated that the ARMC5 protein contains an armadillo repeat domain, suggesting that protein-protein interactions are important for its function. …
ARMC5 Mutations in a Large Cohort of Primary Macronodular ... - PubMed
ARMC5 germline mutations are common in PBMAH. Index cases of mutation carriers show a more severe hypercortisolism and larger adrenals. ARMC5 genotyping may help to identify …
Molecular mechanisms of ARMC5 mutations in adrenal pathophysiology
Since the initial discovery of mutations in the Armadillo-containing repeat protein 5 gene (ARMC5) in primary bilateral macronodular adrenocortical hyperplasia (PBMAH), efforts have been …
含犰狳重复 5（ARMC5）基因 | MCE - MCE-生物活性分子大师
该基因编码 ARM (犰狳/β-连环蛋白样重复序列) 超家族的成员。 ARM 重复序列是一个串联重复的序列基序，长度约为 40 个氨基酸。 这种重复与介导蛋白质-蛋白质相互作用有关。 编码的蛋 …
The mutational landscape of ARMC5 in Primary Bilateral …
2025年2月5日 · Germline inactivating variants of the tumor suppressor gene ARMC5 are responsible for 20–25% of apparently sporadic PBMAH cases and 80% of familial …