atg9在营养丰富的条件下通过高尔基体网络和内体系统迁移，并在自噬诱导的情况下与自噬小体短暂结合。 ATG9通过循环内小体运输可能是自噬小体发生的基本步骤，因为在循环内小体过程 …

2017年1月17日 · Here, we demonstrate that ATG9 is essential for endoplasmic reticulum (ER)-derived autophagosome formation in plants. Through a combination of genetic, in vivo imaging …

2021年11月19日 · The multispanning membrane protein ATG9A is a scramblase that flips phospholipids between the two membrane leaflets, thus contributing to the expansion of the …

Here we report that yeast and human Atg9 are lipid scramblases that translocate phospholipids between outer and inner leaflets of liposomes in vitro. Cryo-EM of fission yeast Atg9 reveals a …

2024年8月1日 · ATG9 vesicles can serve as platforms for the assembly of the autophagy machinery. ATG9 vesicles may form seeds for autophagosomes by establishing contact sites …

2020年10月26日 · Atg9 colocalizes with Atg2 at the expanding edge of the isolation membrane (IM), where Atg2 receives phospholipids from the endoplasmic reticulum (ER). Here we report …

这项研究中，研究人员对人类和酵母中具有未知功能的膜蛋白Atg9进行了研究，他们发现，在体外试验中Atg9能够展现出脂质爬行酶的活性（lipid ...

In this review, we aim to understand various aspects of ATG9 (in invertebrates and plants)/ATG9A (in mammals), including its localization, trafficking, and other functions, in nonneuronal cells …

2017年1月10日 · ATG9 is the only transmembrane protein in the autophagy core machinery and has been proposed to play a key role in directing membrane from donor organelles for …

2021年8月1日 · Recent structural and biochemical analyses have revealed that two mysterious autophagy-related (Atg) proteins, Atg2 and Atg9, are novel types of intermembrane and …