Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The …

2024年12月24日 · CCR2 (C-C Motif Chemokine Receptor 2) is a Protein Coding gene. Diseases associated with CCR2 include Polycystic Lung Disease and Human Immunodeficiency Virus …

CCR2. CCL2 (also known as MCP1) and CCL7 (also known as MCP3) are CC chemokines that bind to CCR2 and mediate Ly6C Bright monocyte recruitment . Although expression of CCR2 …

Macrophages play a critical role in the establishment of a regulated inflammatory response following tissue injury. Following injury, CCR2 + monocytes are recruited from peripheral blood …

2023年1月31日 · C-C chemokine receptor 2 (CCR2) is a dual-function receptor. Similar to other G protein–coupled chemokine receptors, it promotes monocyte infiltration into tissues in …

2023年9月1日 · C–C motif chemokine receptor 2 (CCR2), together with its ligands, especially C–C motif ligand 2 (CCL2), to which CCR2 has the highest affinity, form a noteworthy …

CCR2 refers to a receptor that plays a crucial role in attracting monocytes and macrophages in the context of COPD. Blocking CCR2 has the potential to be a therapeutic strategy for this …

2022年2月24日 · The CCL2-CCR2 axis is currently the most well-studied chemokine pathway in liver disease. CCR2 and its ligands have become therapeutic targets of interest for …

In the present study, we show that TLR2 and TLR4 signaling up-regulates the expression of CCR2 in circulating neutrophils during sepsis, mediating their infiltration and eliciting tissue …

2025年2月8日 · Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response …