Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the human body. [5] In …

2025年3月30日 · CYP1A2 (Cytochrome P450 Family 1 Subfamily A Member 2) is a Protein Coding gene. Diseases associated with CYP1A2 include Major Depressive Disorder and …

Given the predominant role of CYP1A2 in activation of toxic xenobiotics compared with its metabolism of prescription drugs, there are many epidemiological reports examining the role of …

2023年8月1日 · CYP1A2 is part of the drug-metabolizing enzyme family, known as cytochrome P450. CYP1A2 plays an important role in the metabolism of several mental health …

2021年10月1日 · The CYP1A2 gene breaks down caffeine and medications. Check your genetic data to see if you are a fast or slow metabolizer of caffeine.

CYP1A2 is a phase I enzyme that is responsible for converting estrogens into inactive or weak metabolites. Although CYP1A2 is not a direct target site for AIs, the study by Simonsson et al. …

Human cytochrome P450 enzyme 1A2 (CYP1A2) is one of the most important cytochrome P450 (CYP) enzymes in the liver, accounting for 13% to 15% of hepatic CYP enzymes. CYP1A2 …

Both the AHR and CYP1A2 genes are biologically plausible candidates as CYP1A2 metabolizes caffeine and AHR regulates CYP1A2. CYP1A2 is the main caffeine metabolizing enzyme.

2024年4月25日 · Clinical resource with information about CYP1A2, Clozapine response, Genome wide association study identified SNP on 15q24 associated with bladder cancer risk in …

2021年9月9日 · CYP1A2 breaks down toxins and drugs, including caffeine. Learn how the genetics of this enzyme may change how you experience coffee & more.