
Channelrhodopsin - Wikipedia
Channelrhodopsin-1 (ChR1) and Channelrhodopsin-2 (ChR2) from the model organism Chlamydomonas reinhardtii are the first discovered channelrhodopsins. Variants that are …
Channelrhodopsin - an overview | ScienceDirect Topics
The introduction of Channelrhodopsin (ChR2) from the green alga Chlamydomonas reinhardtii has sparked excitement not only in the neurons that express it, but also in many …
Use of channelrhodopsin for activation of CNS neurons - PMC
Channelrhodopsin-2 (ChR2), an algal protein from Chlamydomonas reinhardtii, is a light-activated cation channel capable of inducing depolarization and action potentials in neurons. Three …
Channelrhodopsin-2, a directly light-gated cation-selective …
2003年11月25日 · We demonstrate by functional expression, both in oocytes of Xenopus laevis and mammalian cells, that ChR2 is a directly light-switched cation-selective ion channel. This …
Addgene: Optogenetics Guide
Channelrhodopsin-2 (ChR2), the first widely adopted optogenetic tool, is also a blue light activated cation channel. ChR2 is preferred over ChR1 because ChR2 has higher conductance at …
An engineered channelrhodopsin optimized for axon terminal …
Optogenetic tools such as channelrhodopsin-2 (ChR2) enable the manipulation and mapping of neural circuits. However, ChR2 variants selectively transported down a neuron’s long-range …
A User’s Guide to Channelrhodopsin Variants: Features, Limitations …
Channelrhodopsins (ChRs) are light-activated channels from algae that provide these organisms with fast sensors to visible light for phototaxis. Since its discovery, Channelrhodopsin 2 (ChR2) …
Structural insights into ion conduction by channelrhodopsin 2
2017年11月24日 · The light-gated ion channel channelrhodopsin 2 (ChR2) from Chlamydomonas reinhardtii is a major optogenetic tool. Photon absorption starts a well-characterized …
Channelrhodopsin unchained: Structure and mechanism of a light …
2014年5月1日 · The first identified ChRs were ChR1 [7] and ChR2 [8], naturally hosted by the eyespot of the unicellular alga Chlamydomonas reinhardtii. More recently, up to thirteen ChR …
The form and function of channelrhodopsin | Science - AAAS
2017年9月15日 · Channelrhodopsins (ChRs) are naturally occurring light-gated ion channels that are important for allowing motile algal cells to find suitable light levels. In neuroscience, ChRs …