2020年8月20日 · Leukemia is a heterogeneous group of hematologic malignancies that arise from the dysfunctional proliferation of developing leukocytes. It is classified as either acute or chronic based on the rapidity of proliferation and as myelocytic or lymphocytic based on the cell of origin.

2022年5月18日 · Leukemia starts when the DNA of a single cell in your bone marrow changes (mutates) and can’t develop and function normally. Leukemia cells often behave like abnormal white blood cells. Treatments for leukemia depend on the type of leukemia you have, your age and overall health, and if the leukemia has spread to other organs or tissues.

2024年12月20日 · Leukemia is cancer of the body's blood-forming tissues, including the bone marrow and the lymphatic system. Many types of leukemia exist. Some forms of leukemia are more common in children. Other forms of leukemia occur mostly in adults. Leukemia usually involves the white blood cells.

2014年5月1日 · Leukemia is a clonal proliferation of hematopoietic stem cells in the bone marrow. The four broad subtypes most likely to be encountered by primary care physicians are acute lymphoblastic, acute...

The current approach to classifying leukemia is based on the 2016 World Health Organization (WHO) system (classification for hematopoietic neoplasms). The WHO classification is based on a combination of clinical features and morphology, immunophenotype, and genetic factors.

Chronic lymphocytic leukemia (CLL) clinical features include symptoms seen at presentation, along with features seen due to lymphoid involvement, complications, and extramedullary manifestations.

2022年10月16日 · Leukemia, the most common cancer in children, is a hematological malignancy caused by clonal proliferation of abnormal lymphoid or hematopoietic cells in the bone marrow and/or lymphoid system. Leukemias can be classified into many subtypes based on cell of origin, clinical, phenotypic, and genetic information.

Clinical Features Acute lymphoblastic leukemia (ALL) is a cancer of B or T lymphoblasts defined by the unchecked growth of aberrant, immature lymphocytes and their progenitors. This process ultimately results in the replacement of bone marrow components and other lymphoid organs, giving rise to a distinctive disease pattern.

Leukaemias (or leukemias - U.S. spelling) are cancers of the white blood cells, which begin in the bone marrow. Leukaemias are grouped in two ways: the type of white blood cell affected - lymphoid or myeloid; and how quickly the disease develops and gets worse.

2023年12月7日 · Chronic lymphocytic leukemia (chronic lymphoid leukemia, CLL) is a monoclonal disorder characterized by a progressive accumulation of functionally incompetent lymphocytes (see the...