Copper-64 (64 Cu) is a positron and beta emitting isotope of copper, with applications for molecular radiotherapy and positron emission tomography. Its unusually long half-life (12.7-hours) for a positron-emitting isotope makes it increasingly useful when attached to various ligands, for PET and PET-CT scanning.

Copper-64 is a radioisotope of the chemical element copper. The atomic nucleus of the nuclide 64 Cu consists of the element-specific 29 protons and 35 neutrons; the mass number 64 results from the sum of these nucleons.

2020年6月1日 · 64 Cu-DOTATATE PET/CT is a safe and highly accurate imaging technique to detect SSTR-expressing NETs. In addition, diagnostic performance for 64 Cu-DOTATATE PET/CT is highly reproducible and accurately identifies metastatic versus localized lesions.

This article will describe the synthesis and evaluation of a variety of 64 Cu radiolabeled complexes, oligopeptides, and mAb conjugates which have been, or are close to being, translated to the clinic. Fig. 1.

2025年2月1日 · Copper Cu 64 dotatate injection is used with a PET scan (positron emission tomography) for localization of somatostatin receptor positive neuroendocrine tumors (NETs). Copper Cu 64 dotatate is a radiopharmaceutical.

Detectnet is indicated for use with positron emission tomography (PET) for localization of somatostatin receptor positive neuroendocrine tumors (NETs) in adult patients. Copper Cu 64 dotatate binds to somatostatin receptors.

Copper-64 is a radioisotope used in positron emission tomography (PET) and it has a half-life of 12,7h. It has been used for a long time in different applications (such as hypoxia imaging 64 Cu-ATSM) and more recently as part of the theranostics pair with Copper 67 (for therapy).

2021年10月14日 · Copper-64 is a radiopharmaceutical usually found in the +2 oxidation state as the complexes including the +1 state tend to be more unstable. It is used in molecular radiotherapy and positron emission tomography.

- Only 4 most probable emissions per decay type included. Emissions below 10 keV or 1% excluded. 2. Always wear protective gloves, a lab coat, and safety eyewear to protect the skin and eyes from. 3. Survey work areas before, during, and after work. Work areas may require shielding to keep dose. 4.

Copper-64 (T 1/2 = 12.7 hours; β +: 19%, β −: 38%) has a unique decay profile and can be used for positron emission tomography imaging and radionuclide therapy. The well-established coordination chemistry of copper allows for its reaction with different types of chelator systems.