Probable ATP-dependent RNA helicase DDX41 is an enzyme that in humans is encoded by the DDX41 gene. [5] [6] DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala …

2024年12月24日 · DDX41 (DEAD-Box Helicase 41) is a Protein Coding gene. Diseases associated with DDX41 include Myeloproliferative/Lymphoproliferative Neoplasms, Familial …

2022年8月18日 · These studies strengthen claims that acute myeloid leukemia (AML) with DDX41 MutGL represents a unique clinicopathological entity. It is typically characterized by late‐onset …

2023年12月4日 · Deleterious germ line variants in DDX41 are a common cause of genetic predisposition to hematologic malignancies, particularly myelodysplastic neoplasms (MDS) …

2023年2月2日 · Here we reveal the spectrum of common pathogenic DDX41 germ line variants across multiple ethnicities, estimate the age-related risk of MN development ascribed to …

2024年11月25日 · DDX41-Associated Myeloid Malignancies is a hereditary hematologic malignancy syndrome associated with the DDX41 gene. Learn about DDX41's clinical features …

DDX41-related hematologic malignancy predisposition syndrome is a rare inherited condition. It makes people more likely to develop certain types of blood cancers when they are adults. …

Your cancer sample has shown an alteration in a gene called DDX41. This information sheet will help you understand what this means. This gene alteration may partly explain why you have …

HGNC Approved Gene Symbol: DDX41. Cytogenetic location: 5q35.3 Genomic coordinates (GRCh38) : 5:177,511,577-177,516,961 (from NCBI) The DDX41 gene encodes an RNA …

2023年1月5日 · The DEAD-box RNA helicase 41 gene, DDX41, is frequently mutated in hereditary myeloid neoplasms, identified in 2% of entire patients with AML/MDS. The …