钙火花 - 百度百科
肌肉细胞膜具有许多离子通道，其中一种是电压门控离子通道—二氢吡啶受体DHPR(voltage-gated ion channel Dihydropyridine receptor)。 肌肉细胞膜接受电信号(action potential)后，DHPR开 …
颜宁等科学发文揭示真核电压门控钙离子通道复合物结构-清华大学
Cav1.1（也叫dihydropyridine receptor，DHPR）是最早被鉴定出的电压门控钙离子通道，主要位于骨骼肌细胞的横小管（transverse tubule），是肌肉兴奋收缩偶联（excitation …
Dihydropyridine receptor (DHPR, CACNA1S) congenital myopathy
In skeletal muscle, ECC is performed by the direct coupling of a voltage-gated L-type Ca 2+ channel (dihydropyridine receptor; DHPR) located on the T-tubule with a Ca 2+ release …
DHPR - 维基百科，自由的百科全书
DHPR可能指： 6,7-雙氫喋啶還原酶 （ 英语 ： 6,7-dihydropteridine reductase ） （6,7-dihydropteridine reductase） 二羥基吡啶受體（dihydropyridine receptor），骨骼肌橫小管內的 …
The molecular architecture of dihydropyrindine receptor/L-type …
2015年2月10日 · Dihydropyridine receptor (DHPR), an L-type Ca 2+ channel complex, plays an essential role in muscle contraction, secretion, integration of synaptic input in neurons...
Dihydropteridine reductase deficiency - Wikipedia
Dihydropteridine reductase deficiency (DHPRD) is a genetic disorder affecting the tetrahydrobiopterin (BH4) synthesis pathway, inherited in the autosomal recessive pattern. It is …
1,4 Dihydropyridine Receptor - an overview - ScienceDirect
The 1,4 Dihydropyridine Receptor is a protein complex that senses membrane depolarization in muscle cells, opening a calcium channel to allow calcium entry, influencing muscle …
Cell：最新进展！颜宁/高帅破解药物联合使用的致命副作用机制
2022年11月23日 · LTCCs，也被称为二氢吡啶受体(dihydropyridine receptors, DHPR)，指电压门控Ca2+通道的Cav1亚家族。 LTCCs是由核心α1亚基、细胞外a2d亚基、细胞内b亚基和某些 …
dihydropteridine reductase deficiency
Dihydropteridine reductase (DHPR) deficiency is a severe form of hyperphenylalaninemia (HPA) due to impaired regeneration of tetrahydrobiopterin (BH4), leading to decreased levels of …
Molecular analysis of dihydropteridine reductase deficiency ...
Mutations in the dihydropteridine reductase (DHPR) gene result in hyperphenylalaninaemia and deficiency of various neurotransmitters in the central nervous system, causing severe …