DLG5 Gene - GeneCards | DLG5 Protein | DLG5 Antibody
2024年12月24日 · DLG5 (Discs Large MAGUK Scaffold Protein 5) is a Protein Coding gene. Diseases associated with DLG5 include Yuksel-Vogel-Bauer Syndrome and Short Stature, …
DLG5 - Wikipedia
Disks large homolog 5 is a protein that in humans is encoded by the DLG5 gene. [5][6] This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane …
A double-edged sword: DLG5 in diseases - ScienceDirect
2023年6月1日 · DLG5 has been shown to impact the progression of cancer through direct or indirect interactions with H-catenin, E-cadherin, Vimentin, p53, P21, Cyclin D1, TGF-β1, AKT, …
三阴性乳腺癌(Triple Negative Breast Cancer, TNBC)是乳腺癌的一种特定亚型,因其不表达雌激素受体 (Estrogen Receptor, ER) 、孕酮受体(Progesterone Receptor, PR) 或人表皮生长因子受 …
DLG5 discs large MAGUK scaffold protein 5 [ (human)]
DLG5 gene missense mutation is associated with increased susceptibility to inflammatory bowel diseases in children. The initial report of DLG5 as a novel inflammatory bowel disease (IBD) …
圆盘大 MAGUK 支架蛋白 5（DLG5）基因 | MCE - MCE-生物活性 ...
该基因编码大圆盘 (DLG) 同系物家族的成员，膜相关鸟苷酸激酶 (MAGUK) 超家族的一个子集。 除了 PDZ 和 SH3 结构域之外，MAGUK 蛋白还由催化失活的鸟苷酸激酶结构域组成，并且被认 …
The scaffolding protein DLG5 promotes glioblastoma growth by ...
DLG5 is a novel master regulator of Hedgehog signaling in glioblastoma. DLG5 has unique upregulation and tumor-promoting functions in malignant gliomas. DLG5 is necessary for the …
DLG5 connects cell polarity and Hippo signaling protein ... - PubMed
2016年12月15日 · We report here that DLG5 functions as an evolutionarily conserved scaffold and negative regulator of Hippo signaling, which controls organ size through the modulation of …
A double-edged sword: DLG5 in diseases - PubMed
Discs large homolog 5 (DLG5), a key member of the membrane-associated guanylate kinase (MAGUKs) family, is a scaffold molecule for signal transduction complexes and is responsible …
DLG5 in cell polarity maintenance and cancer development
2014年5月3日 · The polarity protein discs large homolog 5 (DLG5) belongs to a family of molecular scaffolding proteins called Membrane Associated Guanylate Kinases (MAGUKs). As …