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癌症中的E2F转录因子家族 - 知乎 - 知乎专栏
大家好,本期给大家分享的主题是与细胞周期密切相关的 e2f转录因子 家族知识。 e2f转录因子可以通过严格控制细胞周期、维持基因组完整性以及应对 复制压力 和 dna 损伤,在预防肿瘤发 …
细胞周期调控 - 知乎 - 知乎专栏
在e2f的靶点中有两个e型细胞周期蛋白(e1和e2,统称为细胞周期蛋白e),它们结合并激活cdk2。cyclin e-cdk2负责完成rb1的磷酸化,通过释放更多的e2f,促进细胞进入s期所需的蛋白质的合成。
E2F - Wikipedia
E2F is a group of genes that encodes a family of transcription factors (TF) in higher eukaryotes.Three of them are activators: E2F1, 2 and E2F3a.Six others act as repressors: …
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E2F - 维基百科,自由的百科全书
e2f是一组编码高等真核生物 转录因子家族的基因。 其中三个是激活剂:e2f1,e2f2和e2f3a。其他六个充当抑制剂:e2f3b,e2f4,e2f5,e2f6,e2f7a,e2f7b和e2f8。它们都参与哺乳动物细胞中dna …
E2F1 Gene - GeneCards | E2F1 Protein | E2F1 Antibody
2024年12月24日 · E2F1 (E2F Transcription Factor 1) is a Protein Coding gene. Diseases associated with E2F1 include Retinoblastoma and Squamous Cell Carcinoma.Among its …
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At e2f, we power trustworthy AI with high-quality AI training data and expert-driven annotation. Our experts-in-the-loop approach ensures precise AI data labeling, supervised fine-tuning …
The E2F transcription factor 2: What do we know? - PubMed
2021年5月11日 · E2F transcription factor 2 (E2F2) is a member of the E2F family of transcription factors. The classical view is that some E2Fs act as "activators" and others "inhibitors" of cell …
The E2F family: specific functions and overlapping interests
Schematic representation of the E2F transcription factor subgroups, their physiological roles and specific binding partners. (A) The E2F family is divided into at least four subgroups defined by …