Fibrolamellar Carcinoma, or FLC, is a rare cancer of the liver that usually grows in teens and adults under 40 years old. It is unsusal because it occurs in people who have healthy livers. Learn more about how this cancer forms, is treated, and the prognosis.

2022年9月26日 · Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare cancer of the liver. It displays features that make it very different in its behavior and clinical findings from conventional hepatocellular carcinoma (HCC). FL-HCC accounts for a …

2025年2月14日 · Fibrolamellar hepatocellular carcinoma is a distinct histological variant of hepatocellular carcinoma characterized on microscopy by laminated fibrous layers between the tumor cells. It is important as it has different demographics and risk factors compared to "standard" hepatocellular carcinomas.

FLC, also known as fibrolamellar hepatocellular carcinoma, is different from the more common hepatocellular carcinoma (HCC) in that it afflicts young people with normal liver function and no known risk factors.

Fibrolamellar carcinoma (FLC) is a rare variant of hepatocellular carcinoma (HCC), comprising 1%–9% of all HCCs. FLC is a poorly understood malignancy, which seems to be more prevalent in young patients with no underlying liver diseases. The term “fibrolamellar” is derived from thick fibrous collagen bands surrounding the tumor cells.

2022年9月26日 · Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare cancer of the liver. It displays features that make it very different in its behavior and clinical findings from conventional hepatocellular carcinoma (HCC). FL-HCC accounts for a …

2023年2月1日 · FLC tumors are characterized by their unique histologic features and a recently discovered genomic alteration, a chimeric fusion protein found in nearly all tumors. This review article provides the latest advancements in diagnosing, imaging, and managing FLC.

Fibrolamellar carcinoma (FLC) is a variant of hepatocellular carcinoma (HCC), which comprises ∼1%–9% of all HCCs. Although FLC is a variant of HCC, it is distinct from HCC in that it most often affects younger patients (10–35 years of age) with no underlying liver disease.

Fibrolamellar hepatocellular carcinoma (FLM) is a rare tumour that typically presents in young adults. It occurs in non-cirrhotic liver and is usually associated with normal serum alpha-fetoprotein. It is defined by a triad of morphological features: polygonal tumour cells with eosinophilic cytoplasm, prominent macronucleoli and lamellar fibrosis.

Although fibrolamellar carcinoma (FLC) has conventionally been considered to be a histologic variant of hepatocellular carcinoma (HCC), it has more recently been recognized as a distinct...