2001年11月27日 · Flk-2 stimulated by the flt3 ligand has been implicated as both a survival and a proliferative signal of primitive hematopoietic progenitors, acting in synergy with the receptors …

Cluster of differentiation antigen 135 (CD135) also known as fms like tyrosine kinase 3 (FLT-3 with fms standing for "feline McDonough sarcoma"), receptor-type tyrosine-protein kinase …

2001年12月4日 · The loss of Thy-1.1 and gain of Flk-2 expression marks the loss of self-renewal in HSC maturation. The addition of Flk-2 antibody to the lineage mix allows direct isolation of …

6.1.5 cd135 (flk-2) cd135，又称flk-2、flt3和ly-72，是一种iii型酪氨酸激酶受体。cd135既表达在正常的cd34+造血干细胞中，也表达于恶性造血细胞，包括aml、all和cml bc。

1994年10月15日 · The flk-2/flt-3 receptor tyrosine kinase was cloned from a hematopoietic stem cell population and is considered to play a potential role in the developmental fate of the stem …

分析成年小鼠骨髓的KLS亚群的Flk-2和Thy-1.1表达。分离了三个表型和功能上不同的种群：Thy（lo）Flk-2（-）（LT-HSCs），Thy（lo）Flk-2（+）（ST-HSCs）和Thy（-）Flk-2（ …

We investigated the effect of Flk2 deficiency on myelopoiesis, focusing on specification of progenitors between HSC and mature cells. We provide evidence that Flk2 is critical for …

The novel hematopoietic growth factor FLT3 ligand (FL) is the cognate ligand for the FLT3, tyrosine kinase receptor (R), also referred to as FLK-2 and STK-1. The FLT3R belongs to a …

2007年11月16日 · FLT3/FLK2, a member of the receptor tyrosine kinase family, plays a critical role in maintenance of hematopoietic homeostasis, and the constitutively active form of the …

2006年2月1日 · In this study, Flk-2 is most frequently expressed in thyroid tumors, as compared with Flk-1 and c-Kit. The expression of Flk-2 was widely detected in both PTC and FTC, and to …