Glyceraldehyde 3-phosphate dehydrogenase (abbreviated GAPDH) (EC 1.2.1.12) is an enzyme of about 37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules.

Glyceraldehyde-3-phosphate dehydrogenase (G3PD) is a glycolytic enzyme that has also been implicated in a wide variety of functions within neurons. Because of the well-documented role of G3PD as an actin-binding protein, we sought evidence for a G3PD–actin complex in synaptosomes and postsynaptic densities (PSDs).

2024年12月25日 · GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) is a Protein Coding gene. Diseases associated with GAPDH include Microcephaly 21, Primary, Autosomal Recessive and Triosephosphate Isomerase Deficiency. Among its related pathways are glycolysis (BioCyc) and Gluconeogenesis.

Gene ID: 2597, updated on 9-Feb-2025. This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a glycolytic enzyme whose role in cell metabolism and homeostasis is well defined, while its function in pathologic processes needs further elucidation. Depending on the cell context, GAPDH may ...

G3PDH或GAPDH是甘油醛-3-磷酸脱氢酶（ glyceraldehyde-3-phosphate dehydrogenase ）的英文缩写。 该酶是三梭酸循环途径中的一个酶，该酶基因为管家（house keeping）基因，几乎在所有组织中都高水平表达，且它不受含有的部分识别位点、佛波脂等的诱导物质的影响而保持恒定，故被广泛用作抽提total RNA，poly (A)+ RNA，Western blot等实验操作的标准化的内参。 G3PDH或GAPDH是甘油醛-3-磷酸脱氢酶（ glyceraldehyde-3-phosphate dehydrogenase ） …

This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.

2020年4月28日 · Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a highly conserved enzyme within the glycolytic pathway. GAPDH catalyzes the transformation of glyceraldehyde 3-phosphate to glycerate-1, 3-biphosphate, a process accompanied by the production of NADH.

Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (PMID: 11724794, PMID: 3170585). Modulates the organization and assembly of the cytoskeleton (By similarity).

GAPD广布于人体各组织器官，脂肪组织含量较低，肺含酶量约为脂肪组织的10倍，肝、心含量相近，约为脂肪组织的30倍，以骨骼肌、红细胞和肾中的含量最为丰富。 [1] 顺向反应法： 单位表示：生成μmolNADH/L/min23～41U/L. 逆向反应法： 单位表示：氧化μmolNADH/L/min4～28U/L. 经琼脂糖电泳分离血清GAPD同工酶时，可测及三型 同工酶。 血清GAPD同工酶占总活性的百分比及绝对值： 急性心肌梗塞 病人血清GAPD活性的升高早于CK及AST，90%的病人发病后3小时 …