Gap junction alpha-1 protein (GJA1), also known as connexin 43 (Cx43), is a protein that in humans is encoded by the GJA1 gene on chromosome 6. [5] [6] [7] As a connexin, GJA1 is a …

2024年12月25日 · GJA1 (Gap Junction Protein Alpha 1) is a Protein Coding gene. Diseases associated with GJA1 include Oculodentodigital Dysplasia and Syndactyly, Type Iii . Among its …

2018年12月21日 · GJA1 (connexin43) has been predicted as the top key driver of an astrocyte enriched subnetwork associated with Alzheimer's disease (AD). In this study, we …

The GJA1 gene provides instructions for making a protein called gap junction alpha-1 protein. Because this protein is one of a large family of connexin proteins, it is commonly called …

Results identified GJA1 as the downstream target of the alternatively spliced estrogen receptor alpha (ERalpha) variant ERDelta7 action in myometrium. This study demonstrated that GJA1 …

2023年2月18日 · Cx43, also known as GJA1, is the most ubiquitously expressed connexin protein. It is detected in most cell types and involved in many biological processes.

2025年2月9日 · HIV-1 Tat upregulates the expression of GJA1 (Cx43) by binding the promoter of Cx43 in human astrocytes: PubMed

缝隙连接蛋白α1： 该基因是连接蛋白基因家族的成员。编码的蛋白质是间隙连接的一个组成部分，间隙连接由细胞间通道阵列组成，这些通道为低分子量材料从细胞到细胞的扩散提供了途径 …

The GJA1 gene encodes connexin-43 (Cx43), one of the most abundant connexin proteins. Cxs are a family of transmembrane proteins with molecular masses varying from 26 to 60 kD; Cx43 …

2025年1月24日 · GJA1-20k induces focal constriction of mitochondria by actin polymerization, leading to protective mitochondrial fission. Human cervix: HeLa cell line: GJA1-20k presents a …