Histamine H4 receptor - Wikipedia
The histamine H4 receptor, like the other three histamine receptors, is a member of the G protein-coupled receptor superfamily that in humans is encoded by the HRH4 gene. [5][6][7] Unlike …
Structural insights into the agonists binding and receptor ... - Nature
2023年10月20日 · Histamine is a biogenic amine that participates in allergic and inflammatory processes by stimulating histamine receptors. The histamine H 4 receptor (H 4 R) is a …
组胺：过敏“元凶”与肿瘤免疫|组胺|结合|Cancer|细胞|-健康界
2022年12月2日 · 组胺受体属于G蛋白偶联受体 (GPCR)，分为四个亚型：H1R、H2R、H3R和H4R。 其中H3R主要表达于神经细胞，在部分肿瘤细胞和嗜酸性粒细胞有表达。 免疫细胞主 …
Structural basis of ligand recognition and design of ... - Nature
2024年3月20日 · The histamine H4 receptor (H4R) plays key role in immune cell function and is a highly valued target for treating allergic and inflammatory diseases. However, structural...
The histamine H4 receptor: from orphan to the clinic - PubMed
2015年3月31日 · The histamine H4 receptor (H4R) was first noted as a sequence in genomic databases that had features of a class A G-protein coupled receptor. This putative receptor …
浙江大学药学院张海涛课题组在Nature communications报道药物 …
2022年10月24日 · 组胺（Histamine）是一种内源性生物胺，通过作用于G蛋白偶联受体（Gprotein-coupledreceptor，GPCR）家族中的四种不同的组胺受体（H1R、H2R、H3R …
Nat Commun｜龚为民/孙金鹏团队合作揭示整个组胺受体家族的配 …
2024年10月3日 · 许多组胺功能由 G 蛋白偶联组胺受体介导，其中包括四个成员，H1R、H2R、H3R 和 H4R。 事实上，长期以来人们一直认为组胺释放引起的炎症反应是由组胺 H1 受体介导 …
Is the H4 receptor a new drug target for allergies and asthma?
2013年1月1日 · Histamine H4 receptor (H4R) has become a promising target for immuno-inflammatory diseases, such as allergic rhinitis, asthma or dermal allergies. Its distribution …
RPG040Hu01 | 组胺H4受体 (HRH4)重组蛋白 | Homo sapiens …
组胺H4受体 (HRH4)重组蛋白 Recombinant Histamine Receptor H4 (HRH4) GPCR105; GPRv53; H4R; HH4R; H4; AXOR35; BG26; G-protein coupled receptor 105 CD & AM 编 …
组胺受体 H4（HRH4）基因 | MCE
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which …