Peripheral blood lymphocytes (PBLs) express HLA class I antigens and are used for the serologic typing of HLA-A, HLA-B, and HLA-C. HLA class II typing is done with B lymphocytes isolated …

We have isolated the common African HLA-A2 subtype genes from Epstein-Barr virus-transformed B cell lines and have established stable class I reduced transfectants expressing …

HLA-A2 is one of the most frequent HLA class I specificities and thus is extensively studied structurally and functionally. Since its discovery, more than 300 allelic variants of this HLA …

2025年3月30日 · HLA-A (Major Histocompatibility Complex, Class I, A) is a Protein Coding gene. Diseases associated with HLA-A include Severe Cutaneous Adverse Reaction and Hla …

2025年3月16日 · HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The …

HLA-A2 is a negative factor for survival in women with serous adenocarcinomas of the ovary in stages III-IV. This finding has implications for clinical patient management. Association with …

2013年8月19日 · HLA-A*02 is the most prevalent and polymorphic major histocompatibility complex (MHC) allele family in humans. Functional differences have been revealed among …

The class I histocompatibility antigen from human cell membranes has two structural motifs: the membrane-proximal end of the glycoprotein contains two domains with immunoglobulin-folds …

HLA-A2 (A2) is an HLA-A serotype. The serotype identifies the more common HLA-A*0201, *0202, *0203, *0206, and *0207 gene products. A*02 is globally common, but A*0201 is at …

In the present study, we identified human HSP105-derived CTL epitopes restricted by HLA-A2 or HLA-A24 using HLA-transgenic mice (Tgm) and examined whether these epitope-based …