2025年1月2日 · Here, we report that HEY2 (a Hairy/Enhancer-of-split-related transcriptional repressor) is upregulated in hearts of patients with dilated cardiomyopathy. Induced Hey2 …

2024年12月25日 · HEY2 (Hes Related Family BHLH Transcription Factor With YRPW Motif 2) is a Protein Coding gene. Diseases associated with HEY2 include Familial Thoracic Aortic …

Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2) also known as cardiovascular helix-loop-helix factor 1 (CHF1) is a protein that in humans is encoded by the HEY2 gene. [5][6]

通过透射电镜检测分析，Hey2心肌过表达引起线粒体数目减少、膜和嵴等超微结构异常，损害线粒体膜电位（MMP），并伴随ROS升高，导致心肌细胞凋亡（图1）。

2025年1月2日，华东师范大学 钟涛 教授研究合作团队在 Nature Communications 期刊在线发表题为 The transcriptional repressor HEY2 regulates mitochondrial oxidative respiration to …

2025年1月8日 · “The transcriptional repressor HEY2 regulates mitochondrial oxidative respiration to maintain cardiac homeostasis”发表于 Nature Communications （IF 14.7），研究发现 …

2025年1月2日 · Here, we report that HEY2 (a Hairy/Enhancer-of-split-related transcriptional repressor) is upregulated in hearts of patients with dilated cardiomyopathy. Induced Hey2 …

2018年2月8日 · To determine the expression pattern and the regulation of Hey2, we used novel methods including RNAscope and a Hey2CreERT2 knockin line to precisely determine the …

2018年4月10日 · Gene expression profiling and ChIP-seq identifies HEY2, a NOTCH-dependent bHLH class transcription factor 15, as a potential downstream mediator of NKX2-5. …

2025年2月20日 · Data indicate that culture abrogated differential gene expression in part due to gradual loss of canonical Notch activity and HEY2 expression. Common variants at SCN5A …