HGF receptor is a single pass tyrosine kinase receptor essential for embryonic development, organogenesis and wound healing. Hepatocyte growth factor/Scatter Factor (HGF/SF) and its …

Under normal conditions, hepatocyte growth factor (HGF)-induced activation of its cell surface receptor, the Met tyrosine kinase (TK), is tightly regulated by paracrine ligand delivery, ligand …

Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon …

The hepatocyte growth factor receptor, MET, is a proto-oncogene and a prototypical transmembrane tyrosine kinase receptor. Inhere we discuss the MET molecular structure and …

HGFR. Hepatocyte growth factor receptor (HGFR), also known as Met, is an RTK that likely has protective effects against post-MI cardiomyocyte apoptosis. HGF binds its HGFR/Met receptor …

One promising target is the signaling pathway of hepatocyte growth factor (HGF, also known as scatter factor, SF) along with its receptor (HGFR, also known as c-Met). HGF, a potent …

Our data indicate that the Met/HGFR gene is deregulated in a few cases of human leukemia, Burkitt's lymphoma and Hodgkin's disease possibly by chromosomal rearrangements resulting …

Hepatocyte growth factor (HGF) is a pleiotropic cytokine composed of an α-chain and a β-chain, and these chains contain four kringle domains and a serine protease-like structure, …

The HGF receptor (HGFr) is the product of the c-met proto-oncogene, a membrane-spanning tyrosine kinase receptor. The 190-kDa precursor is proteolytically processed within the extra …

2016年6月1日 · Hepatocyte growth factor (HGF) signaling via the MET receptor is essential for embryonic development and tissue repair. On the other hand, deregulated MET signaling …