IL-1α白介素-1α - 知乎 - 知乎专栏
IL-1α 被称为“警报素”（alarmin），在损伤或感染导致的细胞死亡后泄漏到周围环境、以 IL-1R1 依赖性方式激活炎症。 IL-1R1 下游信号通路通过促进趋化因子表达将炎性造血细胞募集到损伤 …
Interleukin 1-alpha - Wikipedia
Interleukin-1 alpha (IL-1 alpha) also known as hematopoietin 1 is a cytokine of the interleukin 1 family that in humans is encoded by the IL1A gene. [5] [6] In general, Interleukin 1 is …
IL-1家族及其各成员研究进展 - 知乎 - 知乎专栏
IL-1家族细胞因子基本都是细胞外分泌，只有只有IL1RN（编码IL-1Ra的基因）编码一种能够通过内质网和高尔基体分泌细胞因子的经典信号肽。 白介素IL-1家族因子可以由多种细胞表达，功 …
IL-1家族信号途径及功能 - 知乎 - 知乎专栏
IL-1是一种非常有效的炎症细胞因子，参与多种免疫反应，包括先天性免疫和适应性免疫。 IL-1α前体基因在包括肾、肝、肺、内皮细胞、星形胶质细胞和胃肠道上皮细胞的细胞中组成性表达。 …
IL1A Gene - GeneCards | IL1A Protein | IL1A Antibody
2024年12月25日 · IL1A (Interleukin 1 Alpha) is a Protein Coding gene. Diseases associated with IL1A include Keratoconjunctivitis Sicca and Silicosis. Among its related pathways are MIF …
Function and regulation of IL-1α in inflammatory diseases and …
IL-1α is constitutively expressed in epithelial, endothelial and stromal cells and can be upregulated in hematopoietic and non- hematopoietic cells by a number of stimuli, including …
Interleukin 1α and the inflammatory process - Nature Immunology
2016年7月19日 · Interleukin 1α (IL-1α) and IL-1β are equally potent inflammatory cytokines that activate the inflammatory process, and their deregulated signaling causes devastating …
Interleukin 1α: a comprehensive review on the role of IL-1α in the ...
The interleukin (IL)-1 family member IL-1α is a ubiquitous and pivotal pro-inflammatory cytokine. The IL-1α precursor is constitutively present in nearly all cell types in health, but is released …
IL1A- 信号通路|蛋白抗体-华美生物
IL1A，即白细胞介素1α，别名IL-1α、Hematopoietin-1、Lymphocyte-Activating Factor (LAF)、Endogenous Pyrogen (EP)、IL1F1等。 它是一种由IL1A基因编码的多效性细胞因子，主要由活 …
白介素 1α（Il1a）基因 | MCE - MCE-生物活性分子大师
Enables cytokine activity and interleukin-1 receptor binding activity. Involved in positive regulation of angiogenesis and positive regulation of vascular endothelial growth factor production.