鸡传染性法氏囊病（Infectious bursal disease，简称IBD）又称鸡传染性腔上囊病，是由鸡传染性法氏囊病毒（Infectious bursal disease virus，简称IBDV）引起、发生在鸡身上的一种常见病害。

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Infectious bursal disease (IBD), also known as Gumboro disease, infectious bursitis, and infectious avian nephrosis, is a highly contagious disease of young chickens and turkeys caused by infectious bursal disease virus (IBDV), [1] characterized by immunosuppression and mortality generally at 3 to 6 weeks of age.

Infectious bursal disease, caused by infectious bursal disease virus, is a disease of young chickens found worldwide. IBDV infects immature B lymphocytes and causes an immune suppression that leads to secondary infections in convalescent birds.

传染性氏囊病（Infectious bursal disease；IBD）为高度接触性感染。 病毒通过被污染的环境、饲料、饮水、垫料、粪便、用具、衣物、昆虫等传播，不经过彻底、有效的隔离，消毒措施很难控制。 鸡传染性法氏囊病病毒为双 RNA 病毒科。 电镜观察表明IBDV有两种不同大小的颗粒，大颗粒约60nm，小颗粒约20nm，均为20面体立体对称结构。 病毒粒子无囊膜，仅由 核酸 和衣壳组成。 核酸为双股双节段RNA， 衣壳 是由一层32个壳粒按5:3:2对称形式排列构成。 病鸡舍中的病 …

鸡传染性囊病病毒 (IBDV)，1986年已被归于双股RNA病毒科 (Birnaviridae)，该科只有一个属，双股RNA病毒属，它的代表种是鱼传染性胰脏坏死病毒。 在确定为双股RNA病毒科和详细研究IBDV有关的形态学、物理、化学特性之前，IBDV曾归属于 小RNA病毒科 或 呼肠孤病毒科。

Infectious bursal disease virus (IBDV) is an important immunosuppressive virus of chickens. The virus is ubiquitous and, under natural conditions, chickens acquire infection by the oral route. IgM+ cells serve as targets for the virus. The most extensive virus …

Infectious bursal disease (IBD), also known as Gumboro disease is a highly contagious and immunosuppressive disease of young chickens caused by IBD virus (IBDV) which is responsible for major economic losses in the poultry industry worldwide.

2021年3月10日 · 染性法氏囊病病毒（Infection bursal disease virus，IBDV）属于双RNA病毒科禽双RNA病毒属，鸡群感染后引发以免疫抑制为主的传染性法氏囊病 (Infectious bursal disease，IBD)。 IBDV基因组包括两条双链RNA，即A、B节段 [1]，其中VP2-VP5由A节段编码。 VP2、VP3是结构蛋白，VP4具有水解酶活性，VP5为非结构蛋白。 其中VP2是病毒衣壳蛋白和主要宿主保护性抗原，与病毒的毒力、细胞嗜性和抗原变异有关 [2-4]。 在病毒VP2 …

2024年4月23日 · 传染性法氏囊病（IBD）是由IBDV引起的危害养禽业健康发展的一种重要免疫抑制病，然而其免疫抑制的分子机制尚未被系统解析。 本研究发现，IBDV感染会触发宿主shutoff。 进而证明，VP5蛋白是IBDV触发shutoff的关键蛋白。