DoD IL4 overview. The Defense Information Systems Agency (DISA) is an agency of the US Department of Defense (DoD) that is responsible for developing and maintaining the DoD …

The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in …

2024年12月25日 · IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway …

STAT6 is so vital for the actions of IL-4 that Stat6-deficient mice phenocopy many of the defects observed with Il4- or Il4ra-deficient mice (e.g., related to Th2 differentiation and Ig class switch).

IL4: Protects controlled unclassified information (CUI) that has a low to moderate impact on national security if compromised. IL5: Adds stricter controls for CUI and data in unclassified …

2021年9月7日 · Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells, …

2003年7月1日 · Acute expression of the IL4 gene by differentiated T H 2 cells is regulated by many positive and negative inducible transcription factors, such as nuclear factor of activated …

2024年12月10日 · IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway …

2012年11月1日 · IL-4 has been extensively studied in the context of its role in immunity. Accumulating evidence indicates, however, that it also plays a critical role in higher functions …

Interleukin-4 (IL4) is a growth factor for both B and T lymphocytes. - High levels of IL4Rs have been observed on tumors derived from such cells. - IL4Rs are also overexpressed on …