2024年12月25日 · LITAF (Lipopolysaccharide Induced TNF Factor) is a Protein Coding gene. Diseases associated with LITAF include Charcot-Marie-Tooth Disease, Demyelinating, Type …

Lipopolysaccharide-induced tumor necrosis factor-alpha factor is a protein that in humans is encoded by the LITAF gene. [5] [6] [7] It is associated with Charcot–Marie–Tooth disease 1C.

2024年1月5日 · The strongest candidate (LITAF) was validated via gene overexpression, KO, and mutation approaches in assays of cell survival. Confocal microscopy and biochemical assays …

We identify the endolysosomal protein LITAF as a mediator of cellular resistance to PFT-induced cell death that is active against both bacterial toxins and the endogenous pore, gasdermin D, a …

LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas. The findings indicate a function of SIMPLE as a regulator of endosomal trafficking and provide evidence …

脂多糖诱导的肿瘤坏死因子： 脂多糖是单核细胞和巨噬细胞的有效刺激物，可引起肿瘤坏死因子-α (TNF-α) 和其他炎症介质的分泌。该基因编码脂多糖诱导的 TNF-α 因子，它是一种 DNA 结合 …

2021年5月15日 · LITAF, also named as p53-inducible gene 7 (PIG7), was initially identified and characterized in the human macrophage cell line THP-1 after stimulation with LPS (Takashiba …

2024年1月5日 · We identify the endolysosomal protein LITAF as a mediator of cellular resistance to PFT-induced cell death that is active against both bacterial toxins and the endogenous pore, …

2017年2月25日 · 就litaf的结构特征和生物学功能的研究进展进行概述。 1litaf的结构特点. litaf在人体中广泛存在,定位于染色体16p13.1~16p12.3, 可编码含228个氨基酸残基的蛋白质分子,具有 …

脂多糖诱导的肿瘤坏死因子（LPS-induced TNF-α,LITAF）,又称p53诱导基因7或溶酶体/晚期内体小膜内在蛋白。 早期研究认为,p53蛋白的164~170位氨基酸肽段导入到人体单核细胞后可抑 …