2024年12月25日 · MCM5 (Minichromosome Maintenance Complex Component 5) is a Protein Coding gene. Diseases associated with MCM5 include Meier-Gorlin Syndrome 8 and Bone …

DNA replication licensing factor MCM5 is a protein that in humans is encoded by the MCM5 gene. [5][6][7] The protein encoded by this gene is structurally very similar to the CDC46 protein from …

2017年2月15日 · We report a patient with a clinical diagnosis of MGORS in whom we detected, by whole-exome sequencing, biallelic variants in MCM5 (minichromosome maintenance complex …

2025年2月10日 · Here we show that zebrafish mcm5 mutation leads to DNA damage in immature T lymphocytes and the immature T cells sensitively undergo rapid cell death. Detailed …

2022年4月19日 · MCM名称来源为minichromosome mantenance，即微小染色体维持基因。 [1] MCM基因家族的六个基因能表达并形成一种六聚体蛋白，其中MCM4/6/7是 MCM复合体 的核 …

2015年7月29日 · Here, using cryo-electron microscopy, we report a near-atomic structure of the MCM2–7 double hexamer purified from yeast G1 chromatin. Our structure shows that two …

2025年3月4日 · Title: Diagnostic performance of minichromosome maintenance 5 (MCM5) in bladder cancer: A systematic review and meta-analysis. The High Expression of …

该基因编码的蛋白质在结构上与酿酒酵母中的 CDC46 蛋白质非常相似，后者是一种参与 DNA 复制起始的蛋白质。 编码的蛋白质是染色质结合蛋白 MCM 家族的成员，并且可以与该家族的 …

2024年3月18日 · Our results indicate that increased levels of Mini chromosome Maintenance Protein 5 (MCM5) are correlated with chemotherapy resistance in patients with GBM.

We performed whole-exome sequencing (WES) in a patient with a clinical diagnosis of MGORS and identified biallelic variants in MCM5. This gene encodes a subunit of the replicative …