MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin). Pyrin is produced in certain white blood cells (neutrophils, eosinophils and monocytes) that play a role in inflammation and in fighting infection.

2021年11月11日 · Familial Mediterranean fever (FMF) is a genetic autoinflammatory disorder that causes recurrent fevers and painful inflammation of your abdomen, chest and joints.

2000年8月8日 · Familial Mediterranean fever (FMF) is divided into two phenotypes: type 1 and type 2. FMF type 1 is characterized by recurrent short episodes of inflammation and serositis including fever, peritonitis, synovitis, pleuritis, and, rarely, pericarditis and meningitis.

2024年12月25日 · MEFV (MEFV Innate Immunity Regulator, Pyrin) is a Protein Coding gene. Diseases associated with MEFV include Familial Mediterranean Fever and Neutrophilic Dermatosis, Acute Febrile . Among its related pathways are …

2023年7月16日 · Familial Mediterranean fever (FMF) is a rare genetic disorder that is primarily seen in some ethnic populations. It is also sometimes called familial paroxysmal polyserositis or recurrent polyserositis. It is characterized by recurrent bouts of fever, appendicitis-like stomach pain, lung inflammation, and swollen, painful joints.

2021年11月11日 · There's no cure for familial Mediterranean fever. However, treatment can help relieve symptoms, prevent attacks and prevent complications caused by inflammation. Medications used to relieve symptoms and prevent attacks of FMF include: Colchicine.

2024年8月27日 · Familial Mediterranean fever (FMF) is a rare genetic disease that runs in families. Most often, it affects people whose ancestors came from countries around the...

Familial Mediterranean fever is caused by variants (also known as mutations) in the MEFV gene. The MEFV gene provides instructions for making a protein called pyrin (also known as marenostrin), which is found in white blood cells.

Familial Mediterranean Fever (FMF) is the oldest and the most frequent autoinflammatory disease. It is a hereditary periodic fever syndrome characterized by self-limited episodes of fever and polyserositis associated with severe long-term complications, such as renal amyloidosis.

The MEFV gene provides instructions for making a protein called pyrin (also known as marenostrin). Learn about this gene and related health conditions.